Lynk Pharmaceuticals Co. Ltd.

Alibaba Group Holding Limited

Zhejiang University

Hangzhou Dianzi University

Xiaodong Li

Zhaokui Wan

Michael Lawrence Vazquez

Yuezhen Xiao

Zongfeng Zhang

Song You

Chen Chen

Hailong Yu

Jian Wu

Fei Wang

Jianhua Yan

Shengyong Lu

Yujun Gao

Mingjun Zhang

Yafei Wang

Yao Peng

Yongli Zhu

Shoukang Wang

Lin Su

Jingyu Wu

Gurmit Grewal

Zhengsheng Yu

Yong Chi

Zhaozhe Gong

Qunxing Huang

Huanyu Zhan

The present disclosure provides a tooth disease classification method based on federated learning (FL), including the following steps: S: acquiring oral information of a user; S: transmitting an oral dental image to a local server for preprocessing; S: performing, by the single local server, model training according to a preprocessed oral dental image set and a model of a cloud master server; S: transmitting trained model parameters to the cloud master server through digital encryption; and S: performing, by each of local servers, fusion and classification according to digitally decrypted model parameters from the cloud master server. The method provided by the present disclosure has accurate classification, does not need to centrally process data, and keeps the oral information strictly secret without privacy disclosure; and meanwhile, the method encrypts the model parameters to further ensure the security.

Tooth disease classification method based on federated learning (FL)

The invention provides novel benzamides of pyrazolyl-amino-pyrimidinyl derivatives of Formula (I) as selective and potent JAK inhibitors for treating various diseases and disorders. The invention also provides pharmaceutical composition of these compounds and methods of their preparation and use thereof.

Benzamides of pyrazolylamino- pyrimidinyl derivatives, and compositions and methods thereof

Provided in the present disclosure is crystal form I of compound 1, and a preparation method thereof and the use thereof.

Crystal form of pyrazolyl-amino-pyrimidinyl derivative, and preparation method therefor and use thereof

The invention provides a novel class of therapeutic agents that are safe and effective TYK2 inhibitors and pharmaceutical compositions of these compounds and methods of preparation and use thereof against various TYK2-mediated diseases and disorders.

TYK2 inhibitors and compositions and methods thereof

Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof

Benzamides of pyrazolylamino-pyrimidinyl derivatives, and compositions and methods thereof

Provided is a novel class of orally and/or topically available, selective and potent JAK inhibitors as safe and effective therapeutics against various diseases and disorders. Also provided is pharmaceutical composition of these compounds and methods of a their preparation and use thereof.

Benzethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof

Methods for performing network configuration on apparatus and network configuration systems are provided. The method includes: receiving a network configuration request sent by a network configuration application, wherein the network configuration request includes hotspot information of an online hotspot; generating a hotspot switching command based on the network configuration request; and sending the hotspot switching command to an apparatus needing network configuration through a network configuration hotspot, to make the apparatus switch a hotspot that the apparatus currently connects to from the network configuration hotspot to the online hotspot.

Methods for performing network configuration on apparatus and network configuration systems

Embodiments of the present disclosure provide methods and devices for accessing a network hotspot device by an unconfigured device. The network hotspot device is configured to create a first hotspot and a second hotspot. The method can include reporting, by the unconfigured device, device information of the unconfigured device to one or more network hotspot devices through the first hotspot of the one or more network hotspot devices for sending the device information to a server. One or more user terminals corresponding to the one or more network hotspot devices sends a configuration request for the unconfigured device to the server, the server determines that the user terminal of which the configuration request is first received by the server is a target user terminal and sends a configuration response message to the target user terminal, the target user terminal enables the unconfigured device to access the second hotspot of a target network hotspot device corresponding to the target user terminal after receiving the configuration response message. The method can also include accessing, by the unconfigured device, the second hotspot of the target network hotspot device.

Method and device for accessing a network hotspot device by an unconfigured device

Methods for performing network configuration on apparatus and network configuration systems are provided. The method includes connecting, by an apparatus, to a network configuration hotspot provided by a router; sending first apparatus information of the apparatus to a server through the network configuration hotspot; receiving a hotspot switching command sent by the server according to the first apparatus information, wherein the hotspot switching command includes hotspot information of an online hotspot; and when a designated network configuration condition is met, connecting to the online hotspot based on the hotspot switching command to complete the network configuration of the apparatus.

The present invention relates to a real-time detection device for municipal solid waste components in an incinerator. The real-time detection device includes: an optical fiber sensor, which faces combustion flame of municipal solid waste combustion region through an observation hole in the incinerator; a spectrometer, which is used for receiving optical signal of the optical fiber sensor; an industrial personal computer, which is used for receiving data of the spectrometer and outputting the municipal solid waste components according to a municipal solid waste component detection program; the municipal solid waste component detection program obtains combustion flame spectral information of municipal solid waste in the incinerator by utilizing the optical fiber sensor and the spectrometer, and detects the municipal solid waste components in real time based on combustion flame spectrum of a single waste component. The present invention further relates to a real-time detection method for municipal solid waste components in an incinerator. Compared with manual classified sampling and detection, the device and method provided by the present invention have the advantages of high efficiency, rapidness, accuracy, capability of being updated in real time; and can realize stable combustion of the municipal solid waste in the incinerator, and reduce emission of pollutants and realize efficient and clean utilization of the municipal solid waste.

Real-time detection device and method for domestic waste components in an incinerator

Growing community of inventors

Hangzhou, China

Xiaodong Li