International Business Machines Corporation

Temasek Life Sciences Laboratory Limited

Xiao Liu

Jayant R Kalagnanam

Kyong Min Yeo

Youngdeok Hwang

Yan Hong

Methods, systems, and computer program products for detection of an arbitrarily-shaped source of an abnormal event via use of a hierarchical reconstruction method are provided herein. A computer-implemented method includes detecting an abnormal event based on analysis of sensor data, wherein said analysis of the sensor data comprises comparing the sensor data to a user-defined threshold; generating a query based on the detected abnormal event; processing the query against one or more given data repositories; executing an inverse model using an output generated in relation to said processing to identify a source of the detected abnormal event, wherein the source comprises an arbitrary shape; and outputting the identified source of the detected abnormal event.

Detection algorithms for distributed emission sources of abnormal events

The present invention is directed to a self-quenching primer comprising; a fluorophore that can be quenched by guanine; an oligonucleotide sequence that forms a hairpin; an oligonucleotide that is a target specific sequence and; use in amplification reactions, particularly in polymerase chain reactions, during which the fluorophore is released thereby emitting fluorescence.

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Singapore, Singapore

Xiao Liu