Chengdu Kanghong Biotechnologies Co., Ltd.

Sichuan Jishengtang Pharmaceutical Cc

Sichuan Jishengtang Pharmaceutical Co., Ltd.

Chengdu Kanghong Pharmaceutical Co., Ltd.

Xiao Ke

Baohua Meng

Xiaofeng Hao

Xiaoping Gao

Yiqian Wang

Pei Chen

The present invention relates to a steroid compound, a use thereof and a preparation method therefor. It is expected that such compound can effectively treat mental and neurological diseases, and has good active efficacy, pharmacokinetic (PK) performance, oral bioavailability, stability, safety, clearance rate, and/or metabolic performance and the like.

Steroid compound, and use thereof and preparation method therefor

The present disclosure relates to a pharmaceutical composition for preventing and treating senile dementia and preparation method thereof. The active ingredients of the pharmaceutical composition are prepared from raw medicinal materials comprising 20-50 parts by weight of Epimedii Folium and 15-55 parts by weight of Poria; or from raw medicinal materials comprising 20-50 parts by weight of Epimedii Folium, 15-55 parts by weight of Poria and 10-55 parts by weight of Acanthopanax, or from raw medicinal materials comprising 20-50 parts by weight of Epimedii Folium, 15-50 parts by weight of Poria, 15-50 parts by weight of Acanthopanax and 6-15 parts by weight of Anemarrhenae Rhizoma.

Pharmaceutical composition for preventing and treating senile dementia and preparation method thereof

The present disclosure relates to a pharmaceutical composition for preventing and treating senile dementia and preparation method thereof. The active ingredients of the pharmaceutical composition are prepared from raw medicinal materials comprising 20-50 parts by weight ofand 15-55 parts by weight of; or from raw medicinal materials comprising 20-50 parts by weight of, 15-55 parts by weight ofand 10-55 parts by weight of, or from raw medicinal materials 20-50 parts by weight of, 15-50 parts by weight of, 15-50 parts by weight ofand 6-15 parts by weight of

Provided are a fusion protein inhibiting angiogenesis or vascular growth, coding sequence thereof, vector comprising the coding sequence, host cell, pharmaceutical composition and use of the fusion protein. The fusion protein of the present invention has high thermostability, and has a dramatic decline in the protein aggregation formation rate in a fermentation process, and a significant increase in the purity and yield of the protein, and has better biological activity.

Fusion protein inhibiting angiogenesis or growth and use thereof

The present invention discloses a humanized anti-human tumor necrosis factor-&#x3b1; antibody and antigen-binding fragment (Fab) thereof. The present invention also discloses a composition comprising the said antibody or antigen-binding fragment (Fab) thereof, and the use of the said antibody or antigen-binding fragment (Fab) thereof in treating the diseases associated with tumor necrosis factor-&#x3b1;.

Growing community of inventors

Sichuan, China

Xiao Ke