Abbvie Inc.

Xianhua Cao

Ravi Chari

Jijie Gu

Supriya Gupta

Camellia Zamiri

Dominic J Ambrosi

Jonathan A Hickson

Yingchun Li

Louie Naumovski

Susan E Lappe

Deanna L Haasch

Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases diseases characterized by aberrant DLL4 and/or VEGF expression or activity.

Anti-DLL4/VEGF dual variable domain immunoglobulin and uses thereof

Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases characterized by aberrant DLL4 and/or VEGF expression or activity.

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Hawthorn Woods, IL, United States of America

Xianhua Cao