Xiamen University

Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Rutgers, the State University of New Jersey

Yang Sheng Tang Company Limited

Beijing University of Chemical Tehcnology

University of Medicine and Dentistry of New Jersey

Xiangzhong Ye

Ningshao Xia

Tong Cheng

Hua Zhu

Yimin Li

Jun Zhang

Wei Wang

Junkai Wan

Shengxiang Ge

Pengfei Gao

Yongliang Yang

Shiyin Zhang

Wenkun Fu

Shangzhi Ji

Xianbo Qiu

Zixin Qiu

Longfa Xu

Provided are an enterovirus D68 (EV-D68) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the EV-D68 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, or a pharmaceutical composition comprising the EV-D68 or a modified form thereof, or the nucleic acid molecule, and use of the EV-D68 or a modified form thereof, or the nucleic acid molecule in the manufacture of a pharmaceutical composition for treating a tumor.

Virus for treatment of tumor

Provided are use of an Echovirus 25 (ECHO25) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the ECHO25 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, in treatment of a tumor in a subject, and in the manufacture of a medicament for treatment a tumor in a subject.

Echovirus for treatment of tumors

Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.

ORF7 deficient varicella virus, vaccine comprising the virus and use thereof

The present invention relates to a detection mechanism for polymerase chain reaction and a polymerase chain reaction device, wherein the detection mechanism comprises at least one excitation module group, each of the excitation module groups comprising two excitation modules for providing excitation light with two wavelengths; an excitation optical fiber, connected to the excitation modules, the excitation optical fiber transmitting the excitation light to at least one reaction tube, each of the reaction tubes receiving excitation light with two wavelengths; a receiving optical fiber, for collecting and transmitting a fluorescent signal from the reaction tube; at least one receiving module group, connected to the receiving optical fiber, each of the receiving module groups comprising two receiving modules, to respectively receive the fluorescent signal of two wavelengths from the same said reaction tube, and convert the fluorescent signal into an electrical signal for output; the detection mechanism is configured to detect the reaction tube in a time division manner, and multiplex the receiving module group to obtain an output result.

Detection mechanism for polymerase chain reaction and polymerase chain reaction device

Growing community of inventors

Beijing, China

Xiangzhong Ye