Bionomics Inc.

Xiangyang Tan

Christilyn Graff

Christopher L Reyes

Peter Chu

Weixing Yang

Weiqun Shen

Jianning Liu

The present disclosure provides an antibody, or an antigen binding fragment thereof, which specifically binds to IL-17A with high affinity. The present disclosure also provides a method for preparing and using said antibody.

Anti-IL-17A antibodies and use thereof

Disclosed herein are antibodies against GPR49 and uses of such antibodies. The antibodies can be monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines expressing such antibodies, nucleic acids and vectors comprising nucleic acids encoding for such antibodies, and methods of blocking cancer stem cell growth with such antibodies.

Methods of blocking cancer stem cell growth

Described herein are antibodies against GPR49 and uses of such antibodies. Various aspects relate to monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines expressing such antibodies, nucleic acids and vectors comprising nucleic acids encoding for such antibodies, and methods of treating cancer with such antibodies.

Methods of inhibiting growth of a colon cancer tumor in a subject by administering monoclonal antibodies to G protein-coupled receptor 49 (GPR49)

Described herein are to antibodies against GPR49 and uses of such antibodies. Various aspects relate to monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines expressing such antibodies, nucleic acids and vectors comprising nucleic acids encoding for such antibodies.

Anti-GPR49 monoclonal antibodies

Methods of inhibiting solid tumor growth by administering GPR49 antibodies

Described herein are antibodies against GPR49 and uses of such antibodies. Various aspects relate to monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines expressing such antibodies, nucleic acids and vectors comprising nucleic acids encoding for such antibodies.

Growing community of inventors

Tewksbury, MA, United States of America

Xiangyang Tan