E.i. Dupont De Nemours and Company

Xiang Feng

Andre R Abad

Nicholas B Duck

Ronald D Flannagan

Lynne Eileen Sims

Theodore W Kahn

The invention provides nucleic acids, and variants and fragments thereof, obtained from strains ofencoding &#x3b4;-endotoxins having pesticidal activity against pests of the order Coleoptera. The invention further provides mutagenized nucleic acids that have been modified to encode endotoxins having improved pesticidal activity and/or altered pest specificity. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant pests.

Genes encoding novel proteins with pesticidal activity against coleopterans

The invention provides nucleic acids, and variants and fragments thereof, obtained from strains ofencoding &#x3b4;-endotoxins having pesticidal activity against pests of the order Coleoptera. The invention further provides mutagenized nucleic acids that have been modified to encode endotoxins having improved pesticidal activity and/or altered pest specificity. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, expression cassettes comprising such nucleic acids, and transformed plants and seeds comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant pests.

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West Des Moines, IA, United States of America

Xiang Feng