Nagoya Institute of Technology

Orthorebirth Co., Ltd.

Xianfeng Yao

Toshihiro Kasuga

Yoshio Ota

Kie Fujikura

Akiko Obata

A fiber wadding for filling bone defects having a flocculent three-dimensional structure is disclosed. The fiber wadding includes a plurality of fibers that contain a biodegradable resin as a principal component and a siloxane. Outside diameter of the plurality of fibers of the wadding is from about 0.05 &#x3bc;m to about 30 &#x3bc;m. Bulk density of the fiber wadding is about 0.005-0.3 g/cm.

Fiber wadding for filling bone defects

A method for producing a flocculent three dimensional fibrous bioactive material using an electrospinning process includes electrospinning a biodegradable fiber by applying an electrical charge to a nozzle of an electrospinning apparatus such that a spinning solution contained therein is made into an electrospun fiber, which is attracted toward a collector container that is electrically grounded and is filled with an ethanol liquid; receiving the electrospun fiber emitted from the nozzle on a surface of the ethanol liquid in the collector container; recovering and drying the electrospun fiber to obtain the flocculent three dimensional fibrous bioactive material having a bulk density of from about 0.01 g/cmto about 0.1 g/cmas measured in accordance with JIS L 1097.

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Kanagawa, Japan

Xianfeng Yao