Jiangsu Academy of Agricultural Sciences

Xialing Zhao

Yanxiu Ni

Jiaqiang Niu

Hongjie Fan

Libin Wen

Xiaoguo Huang

Qi Xiao

Junming Zhou

Haodan Zhu

Dandan Wang

Kongwang He

Wenxian Qian

A() vaccine is provided. For thevaccine, an antigen is a protein with an amino acid sequence shown in SEQ ID NO: 2. A preparation method of thevaccine is provided, including the following steps: mixing a white oil and aluminum stearate to obtain a white oil adjuvant; adding poly sorbate 80 to an aqueous solution of the protein with the amino acid sequence shown in SEQ ID NO: 2, and thoroughly mixing to obtain an antigen solution; and mixing the antigen solution with the white oil adjuvant according to a volume ratio of (0.5-1.5):2, and emulsifying to obtain thevaccine. An animal immunized with thevaccine of the present disclosure can effectively resist the attack ofserotype 2, 3, and 31, with a vaccine protection rate as high as 100%.

() vaccine

Growing community of inventors

Nanjing, China

Xialing Zhao