Dow Corning Corporation

Lts Lohmann Therapie-systeme Ag

Ddp Specialty Electronic Materials US 9, LLC

Dow Silicones Corporation

Dow Corning France Sas

Dow France S.a.s.

Xavier Thomas

Bizhong Zhu

Linda Sue Nartker

Marco Emgenbroich

Elke Klein

Heike Kluth

Eva-Marie Prinz

Eric Jude Joffre

Csilla Kollar

David Clayton Gantner

Joseph Charles McAuliffe

Guillaume Kergosien

Martin Grasmann

Timothy Paul Mitchell

Severine Cauvin

Victor Albert Raul

Simon Toth

Gerald Kenneth Schalau, Ii

Chana Wilson Evans

Gary Lee Loubert

Robert O Huber

Virginie Caprasse

Jean-Luc Garaud

Vinita Pandit

Andre Colas

Morgane Le Meur

Gerald K Schalau

Joseph C Mcauliffe

Gerald K Ii Schalau

The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one polymer and at least additive.

Transdermal therapeutic system for the transdermal administration of guanfacine comprising at least one additive

The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone polymer.

Transdermal therapeutic system for the transdermal administration of guanfacine comprising a silicone polymer

The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone acrylic hybrid polymer.

Transdermal therapeutic system for the transdermal administration of guanfacine comprising a silicone acrylic hybrid polymer

A multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, removing the first solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition. Alternatively, a multi-phase silicone acrylic hybrid visco-elastic composition prepared by polymerizing an ethylenically unsaturated monomer and a silicon-containing pressure sensitive adhesive composition comprising acrylate or methacrylate functionality in a first solvent in the presence of an initiator, adding a processing solvent having a higher boiling point than the first solvent, applying heat to selectively remove a majority of the first solvent, removing the processing solvent, and adding a second solvent to form the multi-phase silicone acrylic hybrid visco-elastic composition. The phase arrangement of the multi-phase silicone acrylic hybrid visco-elastic compositions is selectively controlled by selection of the second solvent.

Multi-phase silicone acrylic hybrid visco-elastic compositions and methods of making same

The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone composition comprising components (a), (d) and at least one of (b) or (c): a. a polyorganosiloxane resin, composed of M and Q units having at least 3 alkenyl groups per molecule, herein after called 'SiVi' groups, b. a polyorganosiloxane compound having at least 2 Si-bonded hydrogen groups on the polysiloxane chain, hereinafter called 'SiH' groups, c. a telechelic polyorganosiloxane compound having terminal Si&#x2014;H groups, and d. a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups, e. a liquid diluent in an amount of from 0% to maximum 40% by weight of composition said components reacting together by hydrosilylation at a temperature below 400 C when they are brought into contact on a substrate and cure to form a continuous film on the substrate. Such formulation can cure quickly at room temperature and can provide good balance between adhesion and tack.

Film forming, silicone containing compositions

The invention provides: a cross-linkable therapeutic composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d) optionally, a solvent, or solvent mixture, wherein the saccharide-siloxane copolymer has the following formula: RaR(3-a)SiO&#x2014;[(SiRRO)m-(SiR2O)n]y-SiR(3-a)Ra that is further formulaically defined and wherein the saccharide-siloxane copolymer is a reaction product of a functionalized organosiloxane polymer and at least one hydroxy-functional saccharide such that the organosiloxane component is covalently linked via a linking group to the saccharide component; films; and methods related thereto. The composition has therapeutic properties. The invention also provides articles of manufacture including topical and transdermal agent delivery patches comprising the novel film-forming composition and/or films.

Silicone film former for delivery of actives

The invention provides a cross-linkable composition comprising a saccharide-siloxane copolymer according to a specified structural formula, a crosslinking agent, and, optionally, solvent. Cross-linked polymeric networks, cured coatings, and articles of manufacture formed from the inventive compositions are also provided, as well as processes and methods of manufacturing the inventive cross-linkable compositions and applications thereof.

Crosslinkable saccharide-siloxane compositions, and networks, coatings and articles formed therefrom

A silicone acrylate hybrid composition includes the reaction product of a silicon-containing pressure sensitive adhesive composition, an ethylenically unsaturated monomer, and an initiator. The silicon-containing pressure sensitive adhesive composition includes acrylate or methacrylate functionality. A method of making the hybrid composition includes polymerizing the ethylenically unsaturated monomer and the silicon-containing pressure sensitive adhesive composition in the presence of the initiator.

Silicone acrylate hybride composition and method of making same

Growing community of inventors

Famars, France

Xavier Thomas