Eth Zurich

Unversität Zürich

Xavier Muller

Philipp Rudolf Von Rohr

Rolf Graf

Pierre-Alain Clavien

Dilmurodjon Eshmuminov

Lucia Bautista Borrego

Philipp Dutkowski

Dustin Becker

Martin Jörg Schuler

Max Leo Hefti

A perfusion loop assembly for ex vivo liver perfusion includes a pump providing perfusion fluid through a line branching at a branching point into a first branch line and a second branch line. The first branch line provides a first portion of the perfusion fluid to the hepatic artery of the liver, the first branch line coupled with a gas exchanger, where the first branch line includes a flow rate sensor and/or a pressure sensor. The second branch line provides a second portion of the perfusion fluid to the portal vein of the liver; the second branch line includes a valve for controlling flow of perfusion fluid into the portal vein. The second branch line includes a flow rate sensor and/or a pressure sensor. A liver chamber assembly holds the liver ex vivo, and an outlet line for the perfusion fluid connects the liver chamber assembly and the pump.

Perfusion loop assembly for an ex-vivo liver perfusion and a method for ex-vivo liver perfusion

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Zurich, Switzerland

Xavier Muller