Endo Pharmaceuticals Inc.

Rxkinetix, Inc.

Endo Pharmaceuticals Colorado, Inc.

Wren Henderson Schauer

Gary Joseph Rosenthal

Timothy C Rodell

Jeffrey B Etter

Claire Coeshott

Adrian C Samaniego

Joan P Blonder

Janice Mary Troha

Victoria Jean Abbas

The present invention provides an immunogen composition and methods for using the same for the development of immunity, and particularly at mucosal sites in a mammal, thereby providing immunity at the site of entry for many major pathogenic organisms and also systemic immunity. The immunogen composition includes an antigen, a biocompatible polymer, and a liquid vehicle, with the biocompatible polymer and liquid vehicle being present in such proportions and interacting in such a way that the immunogen composition exhibits reverse-thermal viscosity behaviour. A delivery vehicle composition including a drug other than an antigen is also provided. Methods are provided for delivering the compositions of the invention to a host.

Delivery vehicle composition and methods for delivering antigens and other drugs

Xerostomia is treated with a sulfur-containing antioxidant, such as N-acetylcysteine. Delivery compositions including polyoxyalkylene block copolymers may be used, which may be formulated to exhibit reverse-thermal viscosity behavior.

Treatment of xerostomia

This present invention provides a therapeutic composition for use in the treatment of mucositis and a method for using such a therapeutic composition. The therapeutic composition includes a pharmaceutical substance effective for treating mucositis formulated with a biocompatible polymer, such as a biocompatible reverse-thermal gelation polymer.

Treatment of mucositis

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Boulder, CO, United States of America

Wren Henderson Schauer