Johnsondiversey, Inc.

Semen Refinement B.v.

Wouter Olthuis

Piet Bergveld

Adrianus J Sprenkels

Loes Irene Segerink

Albert Van Den Berg

Bjorn De Wagenaar

Gerardus Rudolph Langereis

The invention provides a system () for performing sperm analysis and selection based on sperm cell morphology of sperm cells () in a fluid (), the system () comprising: (i) a fluid flow channel () for transport of said fluid (), the fluid flow channel () comprising an inlet () an analyzing zone () configured downstream from said inlet () and comprising a first pair of electrodes () comprising a first intra-electrode distance (dl), a sorting zone () configured downstream from said analyzing zone () and comprising a sorting device (), and outlets (, . . . ) configured downstream from said sorting zone (); (ii) an electric source () configured to provide an electric signal to the first pair of electrodes (); (iii) a measuring device () functionally coupled to the first pair of electrodes () and configured to measure a first impedance as a function of time of the fluid () between the first pair of electrodes, and to provide time-dependent impedance data; wherein the sorting device () is configured to sort sperm cells () by directing the sperm cell () in the sorting zone () to one of the outlets (, . . . ) based on a comparison in a comparison stage of the time dependent impedance data with predefined reference data.

Microfluidic device for selection of semen

A system for characterizing a liquid comprises a sensor for providing an electrical output signal depending on a characteristic of the liquid, and a processing unit for processing the output signal of the sensor to obtain characterizing data of the liquid. The sensor is made as a single sensor/actuator device and can be connected in a plurality of manners to the processing unit. In at least some of these connecting manners the processing unit is adapted to actuate the sensor/actuator device and to process the output signal of the sensor/actuator device to obtain different characterizing data of the liquid.

System and methods for characterizing a liquid

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Enschede, Netherlands

Wouter Olthuis