Postech Foundation

Woo Seong Jeon

Kimoon Kim

Kangkyun Baek

Jin Koo Kang

Dong Hyun Oh

Sang Yong Jon

Dongwoo Kim

Selvapalam Narayanan

Miran Noh

The present disclosure provides a cucurbituril derivative-bonded solid substrate in which cucurbituril derivatives of Formula 1 are covalently bonded to a modified solid substrate of Formula 2. The cucurbituril derivative provides functional groups which can be used to link biomaterials to the substrate. Protein chips, gene chips, and sensors for biomaterial assays having the cucurbituril derivative-bonded solid substrate are also provided.

Cucurbituril derivative-bonded solid substrate and biochip using the same

The present disclosure provides a rotaxane compound that can be used to separate molecules within a linkage layer formed on a solid substrate of a biochip by a predetermined distance. The compound is represented by Formula 1, in which a compound of Formula 3 vertically passes through a cavity of cucurbituril or its derivative of Formula 2. It further provides gene chips, protein chips and sensors for biomaterial assays which use the rotaxane molecules to allow biomaterials to be immobilized on a linkage layer such that they are regularly spaced apart from each other by a predetermined distance.

Rotaxane compound, rotaxane-bonded solid substrate, and biochip using the same

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Pohang, South Korea

Woo Seong Jeon