Korea University Research and Business Foundation

University-Industry Cooperation Group of Kyung Hee University

Shin Poong Pharmaceutical Co., Ltd.

Won Ki Kim

Yongseok Choi

Sumi Song

Jae Chul Lee

Seung Hun Cho

The present invention relates to a pharmaceutical composition or a functional health food comprising a verbenone derivative and pharmaceutically acceptable salts thereof as active ingredients for treating or preventing a neurodegenerative disease. More specifically, the verbenone derivative according to the present invention reduces neuronal cell death and oxidative stress, and is highly effective in preventing ischemic brain damage and inflammatory cell migration in rats, thereby providing the pharmaceutical composition or the functional health food which is useful in treating neurodegenerative diseases.

Pharmaceutical composition containing verbenone derivative for treating or preventing neurodegenerative disease

The present invention relates to a composition containing a fruit extract of. var.as an active ingredient for the prevention and treatment of ischemic cerebrovascular disease. The fruit extract of. var.according to the present invention has a nerve cell-protecting effect, thereby remarkably reducing neurobehavioral impairments and infarct volume due to ischemic cerebrovascular disease. Therefore, it can be provided as a pharmaceutical composition for the prevention or treatment of ischemic cerebrovascular disease, and as a health food for the prevention or improvement of ischemic cerebrovascular disease.

[object Object]

Growing community of inventors

Seoul, South Korea

Won Ki Kim