Maco Pharma S.a.

Forschungsgemeinschaft Der Drk Blutspendedienste E.v.

Wolfram Hubert Walker

Francis Goudaliez

Thierry Verpoort

Frank Tolksdorf

Arnaud Chavatte

Maurice Behague

Harald Mohr

The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.

Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system

The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising: a casing (), a support member () for carrying at least one irradiation bag () containing the biological fluid, a light source () comprising two banks of light () disposed above and below the support member (), and an agitating system () for moving the support member (), the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.

Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process

The invention relates to a method for inactivating pathogens such as bacteria and viruses and/or leucocytes in thrombocyte concentrations by irradiation in flexible containers with ultra-violet light using agitation. The blood product is packaged in a flexible bag to permit the intermixing of the fluid by agitation (tilting, rotation, translation). This is also promoted by the filling of the bag to a maximum 30% of the filling capacity.

Method for irradiating thrombocyte concentrates in flexible containers with ultra-violet light

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Rödermark, Germany

Wolfram Hubert Walker