Troponwerke Gmbh & Co Kg

Bayer Aktiengesellschaft

Troponwerke Gmbh & Co.

Wolfgang Opitz

Haireddin Jacobi

Eugen Etschenberg

Siegfried Raddatz

Bernhard Pelster

Hans-Dieter Dell

Romanis Fruchtmann

Hermann Oediger

Andreas Ohm

Helmut Luchtenberg

Udo Krupka

Walter Gauss

Shinji Maegata

Eugen Etscherberg

Hartmut Kiehne

The invention relates to solid pharmaceutical preparations which have a long-lasting action and are for dihydropyridines in the form of a press coated tablet, and a process for their preparation.

Press coated DHP tablets

New compounds of the formula ##STR1## in which R.sub.1 is an allylamino, acetylamino or propionylamino radical,

1,4-naphthoquinone derivatives having anti-inflammatory action

The invention relates to quinazolinone derivatives and of formula (I) as defined herein and processes for the production of said derivatives. Also included in the invention are pharmaceutical compositions containing a compound of said formula (I) as active ingredient and the use of said compounds and compositions as anti-inflammatory agents.

Quinazolinone derivatives

The invention relates to S-alkyl 3-alkylthiopropionothioates of Formula (I) as defined herein. Also included in the invention are methods for the manufacture of said S-alkylthiopropionothioates, compositions containing them and the use of said compounds and compositions for the treatment of inflammatory processes.

S-Alkyl 3-alkylthiopropionothioate compounds, their production and their

The invention relates to pharmaceutical compositions containing as an active ingredient a dipeptide or an acid salt or a base addition salt thereof or a stereoisomer thereof, said dipeptide being those of the formula

Histolytic agents and their use

The invention relates to compositions containing S-benzyl 3-benzylthiopropionothioate for the treatment of inflammatory processes. Also included in the invention are methods for combating illnesses caused by inflammatory, processes, which methods involve use of medicaments containing said S-benzyl 3-benzylthiopropionothioate.

Antiphlogistic agent and its use

The present invention provides, inter alia, antiphlogistically effective agents, including pharmaceutical compositions containing said agents. Also included are methods for the use of said agents. The active compounds are those of the formula ##STR1## or an ester thereof, in which X denotes a hydrogen atom, an alkyl group, an alkoxy group, an alkylthio group, an alkylsulphinyl or alkylsulphonyl group or a hydroxyl or mercapto group,

Methoxy and methylsulfinylthiolesters

Dehydrooligopeptides, some of which are known, demonstrate histolytic and tumor-resolving activity and may be used in medicaments causing the lysis of animal tissues and/or tumors in warm-blooded animals.

Tumor-resolving and histolytic medicaments and their use

This invention relates to dehydropeptides containing a tryptophan moiety useful as tumour-resolving and/or histolytic medicaments. Also included in the invention are methods for the preparation of said dehydropeptides, compositions containing said dehydropeptides and methods for the use of said dehydropeptides and dehydropeptide compositions.

Dehydropeptide compounds, their production and their medical use

New dehydrooligopepetides which bear, as one terminal substituent, an optionally substituted alkyl or alkenyl, optionally substituted aryl, optionally substituted heterocyclic radical, optionally substituted aralkyl or aralkenyl or a carbamoyl group and as the other terminal substituent a hydroxyl or amino, an optionally substituted alkylamino, optionally substituted arylamino, optionally substituted aralkylamino, an optionally substituted nitrogen-containing heterocyclic radical with five or six ring members optionally containing a further heteroatom, optionally substituted aralkoxy, optionally substituted alkoxy, optionally substituted aryloxy, optionally substituted alkylthio group or optionally substituted hydrazine demonstrate histolytic and tumor-resolving activity. The compounds are prepared by either hydrolyzing or aminolyzing the corresponding 2,4-disubstituted 5(4H)-oxazolones.

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Cologne, Germany

Wolfgang Opitz