Biotest Ag

Wolfgang Möller

Dieter Rudnick

Matthias Germer

Veit Braun

Oliver Maneg

Michael Rodemer

Michael Kretschmar

Herbert Dichtelmueller

Eckhard Flechsig

An antibody preparation suitable for intravenous administration in humans includes IgG, IgA and at least 5% IgM antibodies by weight of the total amount of antibodies. The preparation is prepared from human plasma, has specific complement activating activity, and, in an in vitro assay with human serum suitable to determine the ability of the antibody preparation to activate complement unspecifically, the antibody preparation generates substantially no C5a and/or substantially no C3a. The antibody preparation can have medical uses.

Methods of treating viral infections by administering an antibody preparation comprising IGG, IGA and IGM

IgG, IgA and IgM antibody preparations, method of making and method of use in treatment

An antibody preparation suitable for intravenous administration in humans includes IgG, IgA and at least 5 % IgM antibodies by weight of the total amount of antibodies. The preparation is prepared from human plasma, has specific complement activating activity, and, in an in vitro assay with human serum suitable to determine the ability of the antibody preparation to activate complement unspecifically, the antibody preparation generates substantially no C5a and/or substantially no C3a. The antibody preparation can have medical uses.

Antibody preparations

Growing community of inventors

Oberursel, Germany

Wolfgang Möller