University System of Maryland

Wolfgang Losert

John T Fourkas

William E Bentley

Gregory F Payne

Reza Ghodssi

Gary W Rubloff

Hyunmin Yi

Douglas Stephen English

Li-Qun Wu

Joshua Parker

Patrick Kanold

Mitchell Weikert

Samira Aghayee

Meghan Driscoll

Floyd Bates, Ii

Xiaoyu Sun

Can Guven

The invention provides method of guiding unidirectional movement of a cell comprising exposing the cell to a surface comprising an asymmetric, three-dimensional pattern of one or a plurality of topographical elements for a time period sufficient to bias actin polymerization within the cell. The invention also provides methods of inducing directional movement of a cell, and methods of harnessing an actin wave within a cell. In addition, the invention provides compositions comprising a contact side, wherein at least a portion of the contact side comprises a cell contact portion comprising an asymmetric, three-dimensional pattern of one or a plurality of topographical elements, and methods of inducing healing of a wound of a subject comprising contacting the wound with the composition.

Compositions comprising textured patterns and methods of using the same

A method for displaying a modified phase mask on a spatial light modulator (SLM), including: modifying, by a processor, a phase mask by combining the phase mask with a virtual lens pattern, the virtual lens pattern having a focal length; displaying, by the SLM in communication with the processor, the modified phase mask on the SLM; and projecting, by a light source in communication with the processor, the light source through the SLM to form an intensity pattern at a distance from the SLM corresponding to the focal length of the virtual lens pattern, the intensity pattern being based on the phase mask.

High fidelity configuration for two-photon SLM microscopy

A method is provided for electrochemically depositing a polymer with spatial selectivity. A substrate having a substrate surface is contacted with an aqueous solution containing a selectively insolubilizable polysaccharide, such as chitosan, which is subjected to electrochemically treatment to deposit, with spatial selectivity, the selectively insolubilizable polysaccharide on a patterned electrically conductive portion of the substrate surface.

Spatially selective deposition of polysaccharide layer onto patterned template

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Bethesda, MD, United States of America

Wolfgang Losert