Bayer Aktiengesellschaft

Wolfgang Kreiss

Hans-Georg Rast

Claus Weisemann

G&uuml;nther Eberz

Guenther Eberz

Reinhard Lantzsch

Heinz Pudleiner

Ralf Dujardin

Gerhard Bonse

Eckart Kranz

Joachim Simon

Karlfried Dickore

Reinhard Albers

Klaus Ditgens

Christina Krasemann-Sharma

Henning Dorr

This application claims a method for detecting biologically active substances, comprising the following steps

Method and device for detecting biologically active substances

The invention claimed herein is a kit for detecting biologically active substances on a support, comprising the luminescent marine bacteriain a form stabilized for transport and storage, one or more cultivation media or the individual components of cultivation media for the microorganism wherein the cultivation media containsmg/l tomg/l of aspartic acid, and optionally additives for extending the period of luminescence selected from N-acylhomoserine lactones, dipeptides, oligopeptides, or their biochemical precursors, and boron compounds.

The invention provides moulded items made from thermoplastic polyurethanes (TPUs), in particular medical articles such as central venous catheters which contain a homogeneous distribution of antibiotic substances, a process for the preparation thereof and preparation of the active substance-containing TPUs.

Moulded bodies made of thermoplastic polyurethane containing an active substance

The mixture to be tested for toxic components is first separated into fractions by chromatography. The separated fractions are then contacted with luminescent microorganisms in the chromatographic system itself and the toxicity of the fractions is determined by measurement of the bioluminescence. The chromatographic separation may be carried out either by thin layer chromatography or by column liquid chromatography.

Analytical process for testing mixtures for toxic constituents

A process for the preparation of a herbicidally active 1-amino-1,3,5-triazone-2,4 (1H,3H)-dione of the formula ##STR1## comprising in a first stage at a temperature from about 0.degree. to 100.degree. C. reacting an isocyanate of the formula

Process for the preparation of 1-amino-1,3,5-triazine-2,4(1H,3H)-diones

Growing community of inventors

Bergisch Gladbach, Germany

Wolfgang Kreiss