Add Advanced Drug Delivery Technologies Ltd.

Ipc Process Center Gmbh & Co.

Ipc Process-center Gmbh & Co. Kg

Wolfgang Kempe

Michael Jacob

Marcel Minor

Burkhard Schlütermann

Jörg Dittmann

Wolfram Englisch

Antje Weigt

Marijke Adamse

Karola Bretschneider, Legal Representative

Gunnar Nagel

Constant Van Lookeren Campagne

The invention relates to a method for the production of carrier pellets for pharmaceutical active substances. Likewise, the invention relates to such carrier pellets and also to pharmaceutical formulations containing these. The carrier pellets according to the invention are used for transporting and releasing pharmaceutical active substances, in particular in the human body.

Carrier pellets, method for production thereof and use thereof

The invention relates to pellets and a production process therefor. Pellets comprise at least one oily component, which is either an active component alone or comprises such an active component. The aim of the invention is to ensure that such active components can be provided at elevated concentration in a long-term stable form for subsequent administration or further processing using such inventive pellets. The at least one oily oxidation-sensitive or else readily volatile active component is distributed homogeneously and discretely in a matrix and encapsulated without a core with at least one water-soluble polysaccharide as filmforming agent. The individual pellets have a respective particle size of at least 100 &#x3bc;m, preferably of at least 300 &#x3bc;m.

Pellets and process for production thereof

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Dresden, Germany

Wolfgang Kempe