Ciba Specialty Chemicals Corporation

Roche Diagnostics Operations, Inc.

Wolfgang Jona

Heinz Langhals

Herbert Von Der Eltz

Rupert Herrmann

Peter Sluka

Ursula Klause

Andreas Finke

Federic Donie

The present invention concerns a method for producing microparticles loaded with proteins which is characterized in that the microparticles are loaded in suspension under strongly alkaline conditions. The invention also concerns microparticles which can be produced using this method and their use in a binding test e.g. in an immunoassay.

Method for producing microparticles loaded with proteins

Perylene imide monocarboxylic acids of the general formula I ##STR1## perylene-3,4-dicarboxylic acid imides, perylene imide carboxylic acid derivatives and a process for the preparation of these compounds as well as their use, inter alia, as colourants.

Perylene imide monocarboxylic acids

Perylene hydrazide imides of the general formula I a process for the preparation thereof, the use thereof as detection reagents for carbonyl compounds, protonic acids, acylating agents and metal salts, and also perylene hydrazones II and bi- and tri-fluorophoric perylene bisimides III, the preparation thereof and methods of using them.

Fluorescence-derivatisation of carbonyl compounds-novel carbonyl reagents

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Waldkraiburg, Germany

Wolfgang Jona