Roche Diagnostics Operations, Inc.

Exias Medical Gmbh

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Wolfgang Hofmann

Taghi Noormofidi

Horst Ruether

Wolf-Dietrich Steinboeck

Horst Rüther

Wolf-Dietrich Steinböck

Doris Zahrl

Josef Hindinger

Christoph Pfeiffer

It is provided a measuring cartridge () for measuring at least one constituent of a liquid sample, in particular blood, and for performing quality control, the cartridge comprising: a casing () insertable into a reception opening () of a measuring instrument (), the casing () at least partly surrounding an inner space (); wherein the inner space contains: a measurement cell () comprising a reception space () for the sample and at least one sensor area () with which the sample is in contact when loaded into the reception space (); plural quality control containers () for respectively holding different quality control solutions (); a solution routing system () adapted to selectively route one of the quality control solutions () from the respective quality control container () into the reception space () of the measurement cell ().

Measuring cartridge for measuring a liquid sample

A method for at least partially applying a hydrophilic polymer to a measurement channel of a sensor cartridge is provided, which sensor cartridge can be replaceably inserted in an analyzer. The measurement channel comprises at least one sensor element. The method comprises inserting the sensor cartridge into the analyzer, introducing an aqueous solution containing chitosan or a chitosan derivative into the measurement channel of the sensor cartridge, and following a residence time replacing the aqueous chitosan solution with a gaseous or liquid medium, wherein residues of the chitosan or chitosan derivatives remain on the inside surface of the measurement channel and hydrophilize the surface.

Method for hydrophilizing surfaces of fluidic components and parts containing such components

A method and an apparatus for accelerating the equilibration of a fluid, typically the reference fluid of an analyzer, are provided, the surface of the fluid being in contact with a gas phase. The device can include a cassette, which can be exchangeably inserted into an analyzer and which holds at least one flexible, gas-tight bag, in which the fluid and the gas phase are accommodated. The cassette or the analyzer can include at least one transmitting element, which can be caused to vibrate and which mechanically contacts the flexible bag in order to input mechanical energy into the liquid in at least one wall region.

Method and apparatus for accelerating the equilibration of a fluid

A reagent cartridge which can be exchangeably inserted into an analyzer and having a plurality of reagent bags furnished with connecting lines, each of which may optionally be connected to an input device of the analyzer, and method for operating the analyzer are disclosed. Each reagent bag has an analyzer-controlled multi-way valve with at least two valve positions at the point where the respective connecting line departs, such that the first valve position opens a fluid path between the connecting line and the reagent bag, while the second valve position closes off the reagent bag and opens a fluid path between a ventilation source, e.g. ambient air, and the connecting line. The connecting lines of the reagent bags departing from the multi-way valve open directly into a common rail or a collector valve.

Reagent cartridge

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Graz, Austria

Wolfgang Hofmann