Boehringer Ingelheim Gmbh

Boehringer Ingelheim Kg

C. H. Boehringer Sohn

Boehringer Ingelheim International Gmbh

Wolfgang Hoefke

Herbert Koppe

Wolfram Gaida

Werner Kummer

Helmut Stahle

Kurt Schromm

Ernst-Otto Renth

Anton Mentrup

Walter Losel

Werner Traunecker

Gojko Muacevic

Ludwig Pichler

Gerd Schnorrenberg

Otto Roos

Ingrid Wiedemann

Klaus Stockhaus

Herbert Merz

Richard Reichl

Franz Esser

Walter Kobinger

Christian Lillie

Ilse Streller

Georg Speck

Franz J Kuhn

Dietrich Arndts

Armin Fugner

KoHerbert

Franz Josef Kohn

Gojko Muaceic

Wolfgang Abele, Deceased

Amino acid derivatives of general formula ##STR1## (the definitions of the various symbols being explained in the specification) are suitable for treating high blood pressure and for cardioprotection. The new compounds are prepared and used in the usual way.

Amino acid derivatives and their pharmaceutical use

Aryloxy-aminoalkanes useful as antihypertensive agents are described and disclosed.

Aryloxy-aminoalkanes, and antihypertensive use thereof

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of 1 to 6 carbon atoms, or phenyl(alkyl of 1 to 6 carbon atoms);

Thieno pyridines and their use as anti-hypertensive agents

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of 1 to 6 carbon atoms or phenyl(alkyl of 1 to 6 carbon atoms);

Pyrrolo[2,3-C]pyridines and their use as anti-hypertensive agents

2,3,4,9-tetrahydro beta carboline derivatives, useful as

Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are hydrogen or substituents of various types;

Intermediate 1-alkylenyl-1H-benzimidazol-2-one derivatives

Disclosed are novel compounds having the formula ##STR1## wherein R.sub.1 is a hydrogen or halogen atom, a lower alkyl, lower alkoxy, lower alkoxy lower alkyl, lower alkenyl, lower alkenyl oxy, cyano, hydroxy, trifluoromethyl, nitro, amino, aminocarbonylmethyl, lower monoalkylamino, lower dialkylamino group;

1-aryloxypropanolamines

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of 1 to 6 carbon atoms or phenyl (alkyl of 1 to 6 carbon atoms);

Thieno [3,2,C]pyridines useful as antihypertensives

Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each independently hydrogen, straight or branched alkyl of 1 to 8 carbon atoms or arylmethyl; or

N-[1-(4-Amino-6,7-dialkoxy-2-quinazolinyl)-4-piperidy

This invention relates to substituted imidazo[1,2-a]imidazoles and non-toxic, pharmaceutically acceptable salts thereof. These compounds are useful in relieving pain and in treating hypertonia and coronary diseases.

Imidazo[1,2-a]imidazoles in the treatment of pain, hypertonia and

This invention relates to substituted imidazo[1,2-a]pyrimidines and non-toxic, pharmaceutically acceptable salts thereof. These compounds are useful in relieving pain and in treating hypertonia and coronary diseases.

Substituted imidazo[1,2-a]pyrimidines and pharmaceutical compositions

1-Aryloxy-2-hydroxy-3-((heterocyclic-substituted alkyl)-amino)-propanes

Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, trifluoromethyl, hydroxyl or amino;

Substituted 2-phenylamino-2-imidazolines and salts thereof

1-Aryloxy-2-hydroxy-3[(heterocyclic-substituted alkyl)-amino]propanes

2-(2-Chloro-4-cyclopropyl-phenyl-imino)-imidazolidine, and acid addition

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Budenheim, Germany

Wolfgang Hoefke