Gambro Lundia Ab

Gambro Lunia Ab

Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v.

Wolfgang Freudemann

Bernd Krause

Markus Storr

Markus Hornung

Heinrich Behr

Ralf Flieg

Torsten Knoer

Martin Rempfer

Egbert Müller

Cornelia Winz

Sandra Homeyer

Steffen Wagner

Michael Müller

Christian Oehr

Mehmet Yildirim

Manuela Klotz

Jakob Barz

Ben Elkin

Sarah Panowitz

The present disclosure relates to a method of steam-sterilizing liquid-filled medical devices, e.g., filtration and/or diffusion devices like ultrafilters and capillary dialyzers.

Method for sterilizing water-filled devices

A filter apparatus, a method for the manufacture of the filter apparatus, the use of the filter apparatus in medical, chemical and/or biotechnological applications, and an apparatus for use in the manufacture of the filter apparatus. The filter apparatus has a cylindrical housing and a plurality of hollow fibers. The hollow fibers are combined to form a bundle in the housing and are embedded and held in each case at the end sides in a molding compound. The filtrate space is filled with particles of a chemically or physically active substance.

Filter device combining beads and fibers

A separation material includes a matrix that is bound to a saccharide, enabling the separation from a liquid of substances that selectively bind the saccharide. A method for preparing the separation material and a method for separating substances from a liquid that selectively bind a saccharide of the separation material are also described. A device employs the separation material for separating from a liquid substances that selectively bind to the saccharide of the separation material.

Separation material

A separation material includes a saccharide bound via a linker to a matrix for enabling the separation from a liquid of substances that selectively bind to saccharide moieties. A method for preparing the material, a method for separating from a liquid substances that selective bind to saccharides, and a device including the separation material are also disclosed.

Separation material comprising saccharide ligands

A separating material formed by a solid substrate having a substrate surface, primary or secondary amines coupled to the substrate surface, and a graft polymer formed on the substrate by covalently coupling the primary or secondary amines with a thermally labile radical initiator and subsequently contacting the substrate surface with a solution of one or more polymerizable monomers. Methods for the extracorporeal treatment of blood, blood plasma or blood serum employing the separating material, for affinity adsorption, ion-exchange adsorption, hydrophobic adsorption, or hydrophilic adsorption employing the separating material, and a separating column employing the separating material are also disclosed.

The present invention provides a separating material producable by a) providing a solid substrate, having amino-functional groups coupled to the substrate surface, b) covalently coupling of the amino-functional groups with a thermally labile radical initiator, c) contacting the substrate surface with a solution of polymerizable monomers under conditions, where thermally initiated graft copolymerization of the monomers takes place, to form a structure of adjacent functional polymer chains on the surface of the substrate. The present invention further provides a method for the production of a separating material by a) providing a solid substrate, having aminofunctional groups coupled to the substrate surface, b) covalently coupling of the aminofunctional groups with a thermally labile radical initiator, c) contacting the substrate surface with a solution of polymerizable monomers under conditions, where thermally initiated graft copolymerization of the monomers takes place, to form a structure of adjacent functional polymer chains on the surface of the substrate.

Separating material

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Hechingen, Germany

Wolfgang Freudemann