Dr. Karl Thomae Gmbh

Karl Thomae Gmbh

Other

Wolfgang Eisert

Johannes M Weisenberger

Frank Himmelsbach

Volkhard Austel

Helmut Pieper

Thomas Muller

Thomas Mueller

Armin Heckel

Guenter Linz

Berthold Narr

Josef Nickl

Erich Muller

Rainer Soyka

Gojko Muacevic

Josef Nickl, Deceased

Christopher Meade

Gunter Linz

Gerd Krueger

Peter Gruber

Helmut Franz

Thomas M Uller

G Unter Linz

The specification describes a pharmaceutical combination consisting of dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing this pharmaceutical combination and the use thereof for the controlled prevention of clot formation.

Pharmaceutical compositions containing dipyridamole or mopidamol and

The invention relates to biphenyl derivatives of general formula ##STR1## wherein A to E and X are defined as in claim 1, the stereoisomers thereof, including their mixtures and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties, preferably aggregation-inhibiting effects, pharmaceutical compositions containing these compounds and processes for preparing them.

Biphenyl derivatives, pharmaceutical compositions containing these

The invention relates to cyclic urea derivatives of general formula ##STR1## wherein R.sub.a, R.sub.b, X and Y are as defined herein, pharmaceutical compositions containing the derivatives and processes for preparing them.

Cyclic urea derivatives, pharmaceutical compositions containing these

The invention relates to new arylsulphonamides of the formula ##STR1## (wherein A, B and R.sub.1 to R.sub.6 are as defined in claim 1, the enantiomers, the cis- and trans-isomers thereof where R.sub.4 and R.sub.5 together represent a carbon-carbon bond, and the addition salts thereof, more particularly for pharmaceutical use the physiologically acceptable addition salts thereof with inorganic or organic bases, if R.sub.6 represents a hydroxy group) which have useful pharmacological properties, particularly antithrombotic activities and thromboxane-mediating activities. Furthermore, the new compounds are also thromboxane antagonists (TRA) and thromboxane synthesis inhibitors (TSH). They also have an effect on PGE.sub.2 production.

Arylsulphonamides, pharmaceutical compositions containing these

The invention relates to cyclic imino compounds which have, inter alia, valuable pharmacological properties, especially inhibitory effects on cell aggregation, pharmaceutical compositions which contain these compounds and processes for preparing them.

Cyclic imino derivatives and pharmaceutical compositions containing them

Cyclic urea derivatives and pharmaceutical compositions containing these

The invention relates to cyclic imino derivatives of general formula

2-pyrrolidinones, pharmaceutical compositions containing these compounds

Arylsulphonamides, pharmaceutical compositions containing these compounds

A method for the prevention of adhesions to body organs and parts of organs caused by therapeutic intervention by applying a pharmaceutical composition of tissue plasminogen activator and an aqueous hydroxyethylcellulose hydrogel.

Methods for preventing adhesions to organs and parts of organs by

The invention relates to new arylsulphonamides of the formula ##STR1## (wherein A, B and R.sub.1 to R.sub.6 are as defined in claim 1, the enantiomers, the cis- and trans-isomers thereof where R.sub.4 and R.sub.5 together represent a carbon-carbon bond, and the addition salts thereof, more particularly for pharmaceutical use the physiologically acceptable addition salts thereof with inorganic or organic bases, if R.sub.6 represents a hydroxy group) which have useful pharmacological properties, particularly antithrombotic activities and thromboxane-mediating activities. Furthermore, the new compounds are also thromboxane antagonists (TRA) and thromboxane synthesis inhibitors (TSH) They also have an effect on PGE.sub.2 production.

Arylsulphonamides pharmaceutical compositions containing these compounds

New pyridyl derivatives of the formula ##STR1## wherein R.sub.1 to R.sub.6, A, X and n are as defined herein, the enantiomers thereof, the cis- and trans-isomers thereof if R.sub.4 and R.sub.5 together represent a carbon-carbon bond, and the addition salts thereof. The new pyridyl derivatives have antithrombotic activity and thromboxane-mediated activities. The new compounds are also simultaneously thromboxane antagonists (TRA) and thromboxane synthesis inhibitors (TSH). They also have an effect on PGE.sub.2 -production.

Pyridyl compounds and pharmaceutical compositions containing these

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Biberach, Germany

Wolfgang Eisert