Altana Pharma Ag

Nycomed Gmbh

Wolf-Rüdiger Ulrich

Ernst Sturm

Thomas Martin

Christian Hesslinger

Thomas Fuchss

Raimund Külzer

Rainer Boer

Manfrid Eltze

Andreas Strub

Martin Lehner

The compounds of formula (I) in which R1, R11 and A have the meanings as given in the description are novel effective iNOS inhibitors.

Imidazopyridine derivatives useful as iNOS inhibitors

Novel surfactant protein C esters suitable for preparing pharmaceutical compositions for the treatment of infant respiratory distress syndrome and adult respiratory distress syndrome are described.

Surfactant protein C esters

The compounds of formula I in which R1 is 1&#x2013;4C-alkoxy, A is 1&#x2013;4C-alkylene, B represents 3H-imidazo[4,5-b]pyridin-2-yl, 3H-imidazo[4,5-b]pyridin-2-yl substituted by R2 and/or R3, 9H-purin-8-yl or 9H-purin-8-yl substituted by R4 and/or R5, are effective iNOS inhibitors.

Alkoxypyridine-derivatives

The compounds of formula Iin which M, B1, B2, R1, R2, R6, R7, K1 and K2 have the meanings as indicated in the description are novel active tryptase inhibitors.

Tryptase inhibitors

Compounds of the formula I, in which B1, B2, R1, R2, R6, R7, K1 and K2 are as defined in the description are novel effective tryp-tase inhibitors.

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Constance, Germany

Wolf-Rüdiger Ulrich