November Aktiengesellschaft Gesellschaft Fur Molekulare Medizin

Other

Boehringer Mannheim Gmbh

Exibona Ltd.

November Ag Novus Medicatus Bertling Gesellschaft Fur Molekulare Medizin

November Ab Novus Medicatus Berling Gesellschaft Fur Molekulare Medizin

November Aktiengesellschaft Gesellschaft Fuer Molekulare Medizin

Secutech International Pte. Ltd.

Hueck Folien Gmbh

Responsif Gmbh

Wolf Bertling

Harald Walter

Georg Bauer

Jörg Hassmann

Hans Kosak

Joachim Robert Kalden

Martin Herrmann

Reinhard Voll

Klaus Von Der Mark

Otmar Zoller

Klaus Wanner

Georg Höfner

Jurgen Walter

Christian Reiser

Werner Fr&ouml;r

André Josten

The invention relates to a method for forgery-proof labeling of items, such as credit cards, bank notes and the like, comprising the following steps: (a) applying, to a first layer () that reflects electromagnetic waves, an inert second layer () that is permeable to electromagnetic waves, said second layer having a predetermined thickness, (b) applying, to said second layer (), a third layer () that is formed by metal clusters, and (c) linking the first layer () of the label so produced with the item.

Method for forgery-proof labeling of items, and forgery-proof label

The invention relates to a method for indirectly determining the blood-clotting status. The inventive method comprises the following steps: a) collecting body fluids which contain a protein that can be modified by a vitamin K-dependent &#x3b3;-carboxylase, b) determining at least two concentrations selected from a group consisting of a first concentration C1 of carboxylated protein, a second concentration C3 of decarboxylated protein and an entire concentration C3 of carboxylated and decarboxylated protein, whereby the first concentration C1 is determined using a first antibody A1, the second concentration using a second antibody A2 and the third concentration C3 using a third antibody A3, c) generating a first quotient Q1 from the first C1 and second C2 concentration or generating a second quotient Q2 from the third C3 and first C1 concentration or generating a third quotient Q3 from the third C3 and second concentration C2, whereby a concentration C1, C2, C3 which has not been determined in step b) and which is required for generating the first Q1, the second Q2, or the third quotient Q3 is calculated according to the following relation: C3&#x2212;C2=C1 and d) the first, second or third quotient Q1, Q2, Q3 are correlated with the blood-clotting status.

Method for indirectly determining the blood-clotting status

A method of treating tumors and other conditions in a patient is provided. The method involves administering to the patient a treatment medicament. The medicament contains a first component and a second component. The first component can be a quantity of tumor cells derived from the patient, and the second component is a quantity of annexin, preferably annexin V. The first component and second component are provided in a therapeutically effective treatment amount. Other conditions can also be treated with annexin.

Drug, in particular for modulating the immunological response for the control of viruses, tumors, bacteria and parasites

The invention relates to a method for determining the binding behavior of ligands which specifically bind to target molecules at at least one binding site, whereby the markers are present in a native form and the determination of the concentrations K4 and K5 or of the quantities M2 and M1 is carried out by means of mass spectrometry.

Method for determining the binding behavior of ligands which specifically bind to target molecules

The invention relates to a method for identifying a first polymer () which is bonded to a first phase () that reflects electromagnetic waves. Said method comprises the following steps: (a) bringing the first polymer () into contact with a second polymer (), which is bonded to a solid second phase () by metallic clusters (), said second phase being permeable to electromagnetic waves; (b) irradiating the second phase () with electromagnetic waves; and (c) determining the change in the properties of the reflected electromagnetic waves.

Method and device for identifying a polymer

The invention relates to a synthetic, biologically active molecule for fixing an active ingredient to the virus protein 1 (VP1) of the polyoma virus. According to the invention, an amino acid sequence A1 which is derived from the C-terminal end of virus protein 2 (VP2) or 3 (VP3) of the polyoma virus is bonded to an active ingredient at one of its ends.

Fragments of virus protein 2 or 3 of the polyoma virus, used for transporting active ingredients

The invention relates to a device for receiving and discharging a given amount of liquid, comprising agitating means ( ) arranged on one end (E ) of a capillary ( ) and a diaphragm ( ) in the vicinity of the other end (E ).

Device for receiving and discharging a given amount of liquid

The invention relates to a device for analyzing biological or medical specimens, such as nucleic acids, tissue and the like, in which a closure element is provided for the leaktight closure of a preparation chamber formed in a basic body, the preparation chamber being connected to at least one first duct, through which substance can be introduced into and removed from the preparation chamber when the closure element is closed.

Device for analyzing biological and medical specimens

The invention relates to a device for conducting biochemical and microbiological reactions, comprising a support ( ) for receiving at least one reaction vessel ( ) and a device ( ) for pressing a closing means ( ) sealing the reaction vessel ( ), wherein the closing means ( ) project in closed position in the area surrounded by the reaction vessel ( ). According to the invention, in order to accelerate and simplify reaction, an inner wall of the closing means opposite the reaction vessel ( ) is coated with a molecule ( ) on which a molecule to be detected can be bonded or deposited, wherein the molecule ( ) contains a nucleic acid, an amino acid or a synthetic derivative of a nucleic or amino acid.

Device for conducting biochemical and microbiological reactions

A method for perforating skin including a lancet ( ) held in a lancet holder ( ) which, by means of a spring-loaded element ( ), can be locked in a housing and moved out of the housing. To improve hygiene the invention provides for the lancet holder to be housed in a cup ( ), which can be attached to the housing ( ), and slidably guided in the cup.

Device for perforating skin

Method for purifying and enriching molecules

The invention relates to an agent for detecting chemical substances, comprising: a first polynucleotide or peptide sequence having a first fluorophore molecule, the first end of said sequence being bonded on a solid phase and a second polynucleotide or peptide sequence having a second fluorophore molecule, the second end of said sequence having a group that is sensitive to the chemical substance to be detected. The first polynucleotide or peptide sequence can be hybridized to the second polynucleotide or peptide sequence in such a way that a spatial relationship enabling an interaction betweeen the first and the second fluorophore molecule is produced. When the chemical substance including a physical property is attached to the group and the influence of an external force is exerted on the physical property, the spatial relation can be eliminated, thereby generating or abolishing a fluorescent reaction.

Agent and method for detecting chemical substances

A method for preparing samples for detecting a nucleotide sequence by polymerase chain reaction (PCR) according to which a) an analysis solution is filled into at least one cavity ( ) provided for in a support ( ); b) a lid ( ) configured complementary to the shape of the cavity ( ) is placed onto the support ( ) in such a way that the analysis solution is pushed at least partly into a gap (S) formed between the cavity ( ) and the lid ( ); and c) the gap (S) is sealed by means of at least one seal ( ) provided for near an opening in the cavity ( ).

Method and device for preparing samples for detecting a nucleotide sequence

A method is disclosed for detecting a nucleotide sequence by a polymerase chain reaction, the nucleotide sequence is a constituent of a double-stranded nucleic acid molecule which is in solution and formed of a strand and a counter-strand. A first primer is added to the solution and is complementary to a first segment of the strand located at the 5&prime;-terminus of a central segment. A second primer is added and is complementary to a 5&prime;-terminal second segment of the counter-strand. The solution is brought into contact with a third primer whose 5&prime;-terminal end is bound to a solid phase. The third primer is complementary to the central segment of the strand containing the nucleotide sequence. A reaction vessel is closed which contains the solution. The solution is repeatedly heated and cooled and the nucleic acid molecule is detected in the closed reaction vessel.

Method for detecting a nucleotide sequence

The invention relates to a method for preparing samples for detecting a nucleotide sequence by polymerase chain reaction (PCR), according to which a) an analysis solution is filled into at least one cavity ( ) provided for in a support ( ); b) a lid ( ) configured complementary to the shape of the cavity ( ) is placed onto the support ( ) in such a way that the analysis solution is pushed at least partly into a gap (S) formed between the cavity ( ) and the lid ( ); and c) the gap (S) is sealed by means of at least one seal ( ) provided for near an opening in the cavity ( ).

Growing community of inventors

Erlangen, Germany

Wolf Bertling