Other

Albert Einstein College of Medicine

Dana-Farber-Cancer Institute Inc.

Winfried Edelmann

Raju S Kucherlapati

Jeffrey W Pollard

Richard D Kolodner

Yongwei Zhang

Burkhard Kneitz

Paula E Cohen

Panos Stevis

Methods are disclosed for assembling a plurality of double-stranded DNA fragments into DNA molecules in a single in vitro recombination reaction comprising contacting the plurality of double-stranded DNA fragments with a bacterial extract derived from a RecA deficient bacterial strain so as to assemble the plurality of DNA fragments into DNA molecules.

Cell extract promoted cloning

An animal, e.g., transgenic mouse, in which the MSH5 gene is misexpressed. The animal is useful for screening treatments for a number of conditions. Methods for identifying contraceptive agents are also described.

Methods for identifying compounds which modulate the activity of MSH5

An animal, e.g., transgenic mouse, in which the MSH4 gene is misexpressed. The animal is useful for screening treatments for a number of conditions. Methods for identifying contraceptive agents are also described.

Methods for identifying contraceptive compounds

MSH5 ablated mice and uses therefor

Growing community of inventors

Bronx, NY, United States of America

Winfried Edelmann