Quick-Med Technologies, Inc.

University of Florida Research Foundation Inc

Caphco, Inc.

Other

Hydrocapsule, Inc.

Analytical Research Systems, Inc.

Sigma Scientific LLC

William Toreki

Bernd Liesenfeld

Christopher Batich

Susan Leander

David Moore

Christopher D Batich

Gerald M Olderman

Rustom Sam Kanga

Albina Mikhaylova

Ara Manukian

David N Moore

Larry L Hench

Gregory Scott Schultz

Jon Kenneth West

Michael D Sacks

Guy LaTorre

Marc S Cohen

Kirk Foster

June Wilson

Michael Pitsokos

Guang J Choi

Gregory Staab

David M Moore

David S Lerner

Bruce A Mast

Rudolph Strohschein

James B Estaver

David Mays

Neil H Weinstein

Brendan Barry Wynn

Bernard Christopher Crampsie

Gerald Olderman

An insect olfactometer is described. The olfactometer can be used to study the behavior and response of insects and other living organisms to odorants and airborne chemicals. The olfactometer provides one or more discrete odor zones that do not intersect with each other and are separated by a neutral background control odor zone.

Insect olfactometer

A quad-centric nozzle and system for hydrocapsule encapsulation is disclosed. In at least one embodiment, a quad-centric nozzle is disclosed for encapsulating discrete droplets of liquid by generating a continuous coating or layer of a polymerizable liquid which is substantially immiscible with the core liquid. In at least one embodiment, the quad-centric nozzle includes: a material feed port assembly, a polymer feed port assembly, a first water feed port assembly, a second water feed port assembly and an encapsulated material exit port assembly. In at least one embodiment, the quad-centric nozzle is configured for use in a system for hydrocapsule encapsulation having a pressure control system, a water control system and sparging column, and an ultraviolet exposure chamber system.

Quad-centric nozzle and system for hydrocapsule encapsulation

This invention relates to regenerable antimicrobial coatings with long-lasting efficacy for use in medical applications including implants, medical instruments or devices, and hospital equipment. The same coatings would also have broad utility in the consumer, industrial, and institutional markets. The coating technology would be based on sequestration of hydrogen peroxide (HP) by zinc oxide binders incorporated into the coatings.

Water-borne antimicrobial formulations with hydrogen peroxide

Durable antimicrobial treatments for textiles and other substrates

This invention pertains to a polymeric composition and an antimicrobial composition, each comprising a superabsorbent polymer (SAP), such as used in diapers and sanitary napkins, and peroxide. The superabsorbent material can be made by the process of treating a preformed SAP, such as a crosslinked polyacrylate salt, with a treatment solution comprising hydrogen peroxide dissolved in water, followed by drying. The resulting superabsorbent material has strong antimicrobial activity. Optionally, the treatment solution may also contain a metal salt, including those of zinc, zirconium, and magnesium.

Superabsorbent materials comprising peroxide

A regenerable antimicrobial coating with long-lasting efficacy for use in medical applications including implants, medical instruments or devices, and hospital equipment is disclosed. The regenerable antimicrobial coating is derived from a polymer doped with a metal derivative which has been exposed to vapor-phase hydrogen peroxide, wherein hydrogen peroxide is sequestered in or on the doped polymer.

Regeneration of antimicrobial coatings containing metal derivatives upon exposure to vapor-phase hydrogen peroxide

Regeneration of antimicrobial coatings containing metal derivatives upon exposure to aqueous hydrogen peroxide

This invention pertains to method for imparting a durable antimicrobial activity to substrates, particularly textiles. An acetate-free metal and peroxide antimicrobial treatment formulation is prepared from a metal derivative, hydrogen peroxide and a source of hydroxide ion. The substrate is treated with the composition and dried to afford the treated substrate with antimicrobial activity. Zinc salts, ions, or complexes are preferred.

Antimicrobial textiles comprising peroxide

Anionic polyelectrolytes are used as binding agents to reduce the solubility of cationic antimicrobial polyelectrolytes. Ionic attraction between the anionic stabilizing polyelectrolytes and the antimicrobial cationic polyelectrolytes results in formation of a polyelectrolyte complex (PEC). A treatment liquid comprising a stable colloid, suspension, dispersion, solution, coacervate, or emulsion of the PEC in an aqueous carrier is used to treat an article, thus coating, infiltrating, or infusing the PEC onto or into the article. Subsequent drying results in an antimicrobial article wherein the PEC is bound to the article and is significantly less prone, relative to either of the component polyelectrolytes, to being washed, leached, leaked, extracted, or migrated from the antimicrobial article during use, or when exposed to aqueous fluids or solvents. The antimicrobial article can be further treated with ethylene oxide which enhances its antimicrobial efficacy, its biocompatibility, and its utility in wound dressings, medical devices, clothing, etc.

Polyelectrolyte complex for imparting antimicrobial properties to a substrate

An alcohol- or glycol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises at least one alcohol or glycol and an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or a metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer. Alternatively, the composition is incorporated into or within the substrate.

Disinfectant with durable activity based on alcohol-soluble quaternary ammonium polymers and copolymers

This invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymer chains and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial effect.

Antimicrobial bandage material comprising superabsorbent and non-superabsorbent layers

This invention pertains to method for imparting a durable antimicrobial activity to substrates, particularly textiles. An acetate-free metal and peroxide antimicrobial treatment formulation is prepared by adjusting the pH of a mixture of a metal salt in aqueous hydrogen peroxide to about 7.5. The substrate is treated with the composition and dried to afford the treated substrate with antimicrobial activity. Zinc salts, ions, or complexes are preferred.

A system and method of enhancing the antimicrobial and biofilm-resistant efficacy of surfaces that have cationic polyelectrolytes nonleachably bound thereto in order to impart antimicrobial activity to the surface. The system for enhancing antimicrobial efficacy involves brushing, dipping, wiping, spraying, or storing the surface in a solution containing citrate ion. The method involves treatment of the surface with a solution which enhances the antimicrobial and biofilm-resistant efficacy of the surface, and which prevents a loss of the antimicrobial properties of the surface which may occur over time. Preferably, the enhancement agent is citrate ion and the cationic polyelectrolyte is poly(diallyldimethylammonium chloride), also known as polyDADMAC. The system is particularly beneficial for surfaces of articles such as contact lenses.

System and method for enhancing the efficacy of antimicrobial contact lenses and other surfaces

A method of bonding an antimicrobial cationic polyelectrolyte to the surface of a substrate is described, wherein the antimicrobial thus attached to the substrate provides the substrate with antimicrobial properties, and at least a portion of the bonded antimicrobial is substantially non-leachable during normal conditions of use and storage. A method of manufacturing an antimicrobial material is described which comprises exposure of the substrate to a solution of antimicrobial cationic polyelectrolyte, followed by drying the exposed substrate thoroughly to impart a non-leaching property to at least a portion of the antimicrobial cationic polyelectrolytes.

Method of attaching an antimicrobial cationic polyelectrolyte to the surface of a substrate

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Gainesville, FL, United States of America

William Toreki