Covidien LP

Galvanize Therapeutics, Inc.

Innovital, LLC

Galary, Inc.

Other

Biosense Webster (israel) Ltd.

Specialists on Call, Inc.

Conquest Medical Technologies

William Sanford Krimsky

Jonathan Reuben Waldstreicher

Kevin James Taylor

Roman Turovskiy

Paul Brian Friedrichs

Denise Marie Zarins

Robert J Beetel, Iii

Robert E Neal, Ii

Joshua Benjamin Stopek

Gary Lee Long

Gregory Hiemenz

William J Dickhans

Curt Steven Kothera

Amit Navin Shah

Michael J Kern

Lev Abramovich Koyrakh

Michael Lee

Gregory John Hiemenz

Meir Bar-Tal

Yitzhack Schwartz

Gal Hayam

Robert D Ainsworth

Matityahu Amit

Avi Shalgi

Refael Itah

Brad Alan Snow

Ashish Purekar

Nicholas S Mercer

Seth S Gleiman

Timothy J O'brien

Quim Castellvi

Hai Viet Tran

Luis L Mangual Arbelo

Stephen Robert Selinger

Alexander Marc Nason

Carrie Christine Castellon

Robyn Mi Jung Baek

Armaan G Vachani

Robert J Iii Beetel

Robert E Neal Ii

Robert E Ii Neal

Brad A Snow

Michael J Lee

Devices, systems and methods are provided for treating conditions of the reproductive tract. A number of conditions can afflict the lining and cell layers deeper within the anatomical structures. For example, cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is a condition involving abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer in situ (CIS). Other conditions include human papillomavirus (HPV)-related cervical disease, various endometrial diseases, acute and chronic cervicitis, and various infections (e.g. trichomoniasis) to name a few. In some embodiments, treatments eliminate diseased, damaged, abnormal or otherwise undesired cells leaving the tissue framework intact. This allows the tissue to regenerate in a normal fashion, avoiding the formation of scar tissue. When the tissue framework is left intact, the framework structure repopulates with healthy cells, regenerating the normal tissue without altering the structural properties.

Treatment of the reproductive tract with pulsed electric fields

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, those within the respiratory tract, particularly the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The systems may be used to treat pathogens, such as bacteria and viruses, particularly coronaviruses.

Immunostimulation in the treatment of viral infection

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

Methods, apparatuses, and systems for the treatment of pulmonary disorders

Disclosed are systems, devices, and methods for navigating a tool inside a luminal network. An exemplary method includes receiving image data of a patient's chest, identifying the patient's lungs, determining locations of a luminal network in the patient's lungs, identifying a target location in the patient's lungs, generating a pathway to the target location, generating a three-dimensional (3D) model of the patient's lungs, the 3D model showing the luminal network in the patient's lungs and the pathway to the target location, determining a location of a tool based on an electromagnetic (EM) sensor included in the tool as the tool is navigated within the patient's chest, displaying a view of the 3D model showing the determined location of the tool, receiving cone beam computed tomography (CBCT) image data of the patient's chest, updating the 3D model based on the CBCT image data, and displaying a view of the updated 3D model.

Integration of multiple data sources for localization and navigation

A surgical system includes a bronchoscope, an extended working channel defining an elongated passageway and adapted to extend through the bronchoscope, and a valve in fluid communication with the passageway of the extended working channel. The surgical system further includes an elongated surgical instrument configured and dimensioned to be inserted through the extended working channel. During operation, a fluid is able to flow from the valve and through the extended working channel such that the fluid travels within an annular area surrounding the elongated surgical instrument positioned within the extended working channel.

Rail system for use with a bronchoscope

A method and system for instilling a medium into portions of a luminal network is provided. The method includes generating a model of a luminal network based on images of the luminal network, determining a location of a treatment target in the luminal network, navigating a bronchoscope through the bronchial tree to a target, guiding a catheter through the bronchoscope, dispensing medium to the target from a distal end of the catheter, and removing a quantity of medium from the luminal network.

System and method for cleansing segments of a luminal network

Provided in accordance with the present disclosure is a diagnostic and a therapeutic bronchoscopy system for localized delivery of medication within the lungs. Specifically, systems and methods are disclosed for creating a functional and anatomical map of the lungs, diagnosing a condition within the lungs, generating a treatment plan for a target site within the lungs, navigating to the target site, administering a treatment directly to the target site for immediate absorption within the target site, and assessing the efficacy of the treatment.

Systems and methods for navigational bronchoscopy and selective drug delivery

Disclosed are systems, devices, and methods for performing treatment along a lumen network, an exemplary method comprising receiving image data of a patient's lungs, mapping one or more luminal networks inside the patient's lungs based on the received image data, identifying a treatment target in the image data, determining a luminal pathway to the treatment target via at least one of the luminal networks, configuring treatment parameters for treatment of the treatment target and at least one of the luminal networks, navigating a tool inside at least one of the luminal networks to the treatment target, treating the treatment target with a primary treatment modality, and treating the luminal pathway of at least one of the luminal networks leading to or from the treatment target with a secondary treatment modality.

System and method of performing treatment along a lumen network

A medical device and methods for altering lung volume are disclosed. The medical device includes a coil formed of a biodegradable material including a first bioabsorbable material that is configured to deactivate a portion of a lung as the coil degrades. The method includes positioning a first coil adjacent a first target within a patient and permitting the first coil to degenerate such that a first bioabsorbable material deactivates a first portion of a lung. The first coil is formed of a biodegradable material and includes the first bioabsorbable material.

Methods and devices for altering lung volume

Energy is transmitted to a body lumen or passageway in the form of pulsed electric fields (PEFs) and in a manner which provides focal therapy. In some embodiments, PEFs are delivered through independent electrically active electrodes of an energy delivery body, typically in a monopolar fashion. Such delivery concentrates the electrical energy over a smaller surface area, resulting in stronger effects than delivery through an electrode extending circumferentially around the lumen or passageway. It also forces the electrical energy to be delivered in a staged regional approach, mitigating the effect of preferential current pathways through the surrounding tissue. Focal delivery of PEFs can provide increased tissue lethality by employing precise timing and sequencing of energy delivery to the electrodes.

Optimization of energy delivery for various applications

A system for monitoring an approach to a target includes a luminal device including a distal portion, a sensor coupled to the distal portion of the luminal device, and a surgical instrument including one or more indicators having a detectable property located along at least a portion of the surgical instrument. The luminal device is configured to be inserted into a patient, and the distal portion of the luminal device is configured to be guided proximate a target. The sensor is configured to sense the detectable property of the one or more indicators. The surgical instrument is configured to be guided through the luminal device.

System, apparatus, and method for navigating to a medical target

Surgical system having a guide catheter including a fluid passageway

A system and method for navigating to a target site in a patient is provided. The system includes an extended working channel and a tool usable with an electromagnetic navigation system. In particular, the extended working channel and the tool contain an electromagnetic sensor configured to provide location information within a patient of the extended working channel and the tool to the electromagnetic navigation system. The distance from the tool and the target site can then be determined and displayed to a clinician on a display device.

System and method to access lung tissue

Growing community of inventors

Forest Hill, MD, United States of America

William Sanford Krimsky