Topera, Inc.

William Robert Macneil

Ruchir Sehra

Carey Robert Briggs

Heather A Drury

Christopher Todd Schuster

Provided are a system and method of generating an aggregated stability map of one or more rotational sources associated with a heart rhythm disorder. In accordance therewith, a plurality of rotational area profile maps is accessed for a plurality of analysis intervals. Each of the profile maps includes rotation intensity values for a plurality of locations associated with rotation of the one or more rotational sources. An aggregated stability map is generated based on the profile maps, wherein the stability map includes a plurality of locations. Each location includes a rotation intensity value based at least on a filter number of highest rotation intensity values from corresponding locations of the profile maps, the filter number being automatically determined from a plurality of filter numbers such that the plurality of profile maps as filtered includes a predetermined number of rotation intensity values in excess of a threshold intensity value.

System and method to define an aggregated stability map of a rotational source over a plurality of time intervals associated with a biological rhythm disorder

Provided is a system and method of generating an aggregated stability map of one or more rotational sources associated with a heart rhythm disorder. In accordance therewith, a plurality of rotational area profile maps is accessed for a plurality of analysis intervals. Each of the rotational area profile maps includes rotation intensity values for a plurality of locations associated with rotation of the one or more rotational sources. Thereafter, an aggregated stability map is generated map based on the plurality of rotational area profile maps, wherein the aggregated stability map includes a plurality of locations. Each location includes a rotation intensity value based at least on a filter level of highest rotation intensity values for that location from corresponding locations of the plurality of rotational area profile maps.

A system to generate a representation of a rhythm disorder that includes identifying remote or polar sources associated with a cardiac rhythm disorder is disclosed. The system includes generating a representation based on the cardiac information signals received from the sensors by transformation of spline-sensor locations of the catheter to x-y coordinate pairs of locations. A first offset is determined resulting from a perturbation to corresponding x-y coordinate pairs of locations associated with the representation, the first offset displacing coordinate pairs of sensor locations of the representation at least one unit of displacement in a first direction. A remote source associated with a cardiac rhythm disorder is identified when activations associated with the cardiac information signals rotate in sequence at least once, or emanate centrifugally for at least a first time period, the source being identified based on the representation as displaced. A corresponding method and computer-readable medium are also disclosed.

System and method to identify remote sources associated with a biological rhythm disorder

An example system and method of defining a rotational source associated with a heart rhythm disorder are disclosed. A plurality of center locations of wave fronts are calculated at a plurality of time points associated with the heart rhythm disorder. A rotational path that connects the plurality of center locations is then determined. Thereafter, a clinical representation that identifies a region of heart tissue associated with the rotational path is generated. The system and method can also determine a likely core associated with the rotational path. A plurality of relative diffusion shapes associated with the plurality of the center locations is calculated. A plurality of intersecting points of a smallest relative diffusion shape and other relative diffusion shapes is determined within the rotational path. A bounded polygon of the intersecting points is defined as the likely core.

System and method to define a rotational source associated with a biological rhythm disorder

An example system and method of determining a likely core of a rotational source associated with a heart rhythm disorder are disclosed. A plurality of relative diffusion shapes associated with wave fronts is calculated at a plurality of time points associated with the rotational source. The wave fronts associated with heart signals. A plurality of intersecting points of a smallest relative diffusion shape and other relative diffusion shapes is determined. A bounded polygon of the intersecting points is defined as the likely core.

An example system and method of defining a rotational source associated with a heart rhythm disorder are disclosed. A plurality of center locations of wave fronts are calculated at a plurality of time points associated with the heart rhythm disorder. A rotational path that connects the plurality of center locations is then determined. The system and method can also determine a likely core associated with the rotational path. A plurality of relative diffusion shapes associated with the plurality of the center locations is calculated. A plurality of intersecting points of a smallest relative diffusion shape and other relative diffusion shapes is determined within the rotational path. A bounded polygon of the intersecting points is defined as the likely core.

Growing community of inventors

Oakville, MO, United States of America

William Robert Macneil