Albert Einstein College of Medicine

Duke University

William R Jacobs

Steven A Porcelli

Betsy C Herold

Christopher Petro

Garnett Kelsoe

Pablo A Gonzalez Munoz

Masayuki Kuraoka

Miriam Braunstein

Lawrence Leung

Volker Briken

Clare Burn

Anna Paula De Oliveira

Regy Lukose

Provided are antibodies and antigen-binding fragments which bind to herpes simplex virus-2 (HSV-2), methods of use employing the antibodies and/or antigen-binding fragments, and pharmaceutical compositions comprising the antibodies and/or antigen-binding fragments.

Monoclonal antibodies for prevention and treatment of herpes simplex viral infections

A genetically modified mammalian cell and genetically modified mammalian cell line comprise a recombination sequence inserted in a target locus on a chromosome of the mammalian cell genome, wherein the recombination sequence comprises Bxb1attB sequence from. A transgenic mammalian cell and transgenic mammalian cell line comprise a heterologous nucleic acid stably integrated in a target locus on a chromosome of the mammalian genome, wherein the heterologous nucleic comprises a heterologous gene configured for expression by the transgenic mammalian cell.

Attb cell line, transgenic cell lines derived therefrom, and methods of making the same

Growing community of inventors

Bronx, NY, United States of America

William R Jacobs