Discovery Partners International, Inc.

Irori

William R Ewing

John E Lillig

Michael P Nova

Yozo Satoda

Hanan Potash

Rhett L Affleck

John F Bridwell

Gordon W Hudson

Robert K Neeper

Kanchana Sanjaya Karunaratne

Kanchana Sanjaya Gunesekera Karunaratne

Donald O'Neil

Card carrying an array of compounds

Automated drug discovery protocols, or partially automated protocols, in which matrices with memories serve as the platform on which all manipulations are performed or serve as the repository of information that is transferred to other memories as the synthesized compounds are processed and screened. Also provided are automated drug discovery units for use in the protocols. The units provide a means for seamless data tracking and include instrumentation and vials with memories for information transfer to other memories in a unit. The units, which are provided herein, include some or all of the following: an automated or manual sorter, microvessels, which contain memories, an automated or semi-automated synthesizer, a microvessel washer/dryer, a manual or automated cleaver for removing compounds from the matrix with memory microvessels, and associated software. The memories may be any of any type, including electromagnetically encodable memories and optical memories, or combinations thereof. The memories may be pre-encoded or may be encodabie during, after or before processing. Also provided are manual and automated methods for sorting matrices with memories.

Automated sorting system for matrices with memory

Automated drug discovery protocols, or partially automated protocols, in which matrices-with-memories serve as the platform on which all manipulations are performed or serve as the repository of information that is transferred to other memories as the synthesized compounds are processed and screened. Also provided are automated drug discovery units for use in the protocols. The units provide for seamless data tracking and include instrumentation and vials with memories for information transfer to other memories in a unit. The units, which are provided herein, include some or all of the following: an automated or manual sorter, microreactors and microvessels, which contain memories, an automated or semi-automated synthesizer, a microreactor washer/dryer, a manual or automated cleaver with a valved U-tube outlet for removing compounds from the matrix-with-memory microreactors, and associated software. The memories may be any of any type, including electromagnetically encodable memories and optical memories, or combinations thereof. The memories may be pre-encoded or may be encodable during, after or before processing. Also provided are manual and automated methods for sorting matrices with memories.

Matrices with memories in automated drug discovery and units therefor

Growing community of inventors

Encinitas, CA, United States of America

William R Ewing