Cellectar, Inc.

General Electric Company

Cellectar Biosciences, Inc.

William R Clarke

Jamey Paul Weichert

Anatoly Pinchuk

Marc Longino

Irawati Kandela

Jiang Hsieh

Anne Lindsay Hall

Michael John Barber

Brian John Kost

Michael A Juhl

Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem cells in humans.

Ether and alkyl phospholipid compounds for treating cancer and imaging and detection of cancer

The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds. A preferred compound of the present invention has the following structural formula: 

Fluorescent phospholipid ether compounds, compositions, and methods of use

A computer readable storage medium having a computer program stored thereon and representing a set of instructions that when executed by a computer causes the computer to calculate a mapping function that provides a location of each sub-volume of an imaging volume as a function of time from ultrasound data and determine a respective acquisition window for each sub-volume of the imaging volume from the mapping function. The instructions also cause the computer to reconstruct an image of the imaging volume substantially free of motion artifacts from imaging data acquired from the imaging volume.

Apparatus and method for reconstructing an image with reduced motion artifacts

The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds. A preferred compound of the present invention has the following structural formula: (I) 

Motion data is acquired simultaneously and in real-time with image data. The motion data provides accurate and near-instant information as to the state and position of an object prone to motion. The present invention is particularly applicable for cardiac CT or MR imaging and other physiologically gated acquisitions. In the context of cardiac imaging, the motion data includes information regarding size and location of the heart during the cardiac phases (diastole, systole, etc.) during each cardiac cycle.

Method and apparatus to compensate imaging data with simultaneously acquired motion data

The invention generally relates to novel fluorescent phospholipid compounds and compositions comprising these compounds. A preferred compound of the present invention has the following structural formula: 

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Colgate, WI, United States of America

William R Clarke