General Electric Company

General Electric Corporation Gmbh

Global Life Sciences Solutions Operations UK Ltd

William Patrick Waters

Kristopher John Frutschy

John Richard Nelson

Weston Blaine Griffin

Christopher Michael Puleo

Erik Leeming Kvam

Erin Jean Finehout

Gregory Andrew Grossmann

Ryan Charles Heller

Jaydeep Roy

Narayan Subramanian

Phillip Alexander Shoemaker

Daniel Qi Tan

Richard Scott Bourgeois

John Raymond Krahn

William Hubert Schank

Reza Sarrafi-Nour

Philip Alexander Shoemaker

Stefan Rakuff

Mohamed Sakami

James Thorpe Browell

Kanthi Latha Bhamidipati

Sandor Istvan Hollo

Keven Peat

Stephen Brooker

Mao Leng

Provided herein are methods for the collection and amplification of circulating nucleic acids from a non-celluar fraction of a biological sample. Circulating nucleic acids are extracted from the non-cellular fraction and are circularized to generate single-stranded nucleic acid circles, which are then subsequently amplified by rolling circular amplification using random primers to produce an amplified library. Devices for the collection of a non-cellular fraction from a biological sample are also provided. The device includes a filtration membrane and a dry solid matrix, which is in direct contact with the filtration membrane.

Method and device for collection and amplification of circulating nucleic acids

A high-throughput system for processing biological material that comprises: a tray that supports a functionally-closed fluid path subsystem comprising, a vessel for containing and enabling the biological material to separate into two or more distinct submaterials; one or more receptacles to receive one or more of the submaterials from the vessel; a filtration device; a conduit through which one or more submaterials are transported between at least the vessel and the filtration device; and a first engagement structure; a processing unit comprising, a pumping device for moving one or more of the submaterials between at least the vessel and the filtration device via the conduit; a second engagement structure corresponding to the first engagement structure; a locking mechanism for at least temporarily holding the tray in a fixed position relative to the processing unit; a control device that automatically starts and stops the pumping device in response to one or more commands.

High-throughput methods and systems for processing biological materials

Provided herein are methods for the collection and amplification of circulating nucleic acids from a non-cellular fraction of a biological sample. Circulating nucleic acids are extracted from the non-cellular fraction and are circularized to generate single-stranded nucleic acid circles, which are then subsequently amplified by rolling circular amplification using random primers to produce an amplified library. Devices for the collection of a non-cellular fraction from a biological sample are also provided. The device includes a filtration membrane and a dry solid matrix, which is in direct contact with the filtration membrane.

In accordance with an embodiment of the invention, an assembly of tubular cell insulator casings is provided. The assembly includes a plurality of tubular cell insulator casings, wherein each cell insulator casing is open at a top end and configured to surround at least one of a plurality of electrically interconnected electrochemical cells, wherein said plurality of tubular cell insulator casings comprises a monolithic unit. The battery pack also includes a plurality of insulator plugs and a sump plate configured to support said plurality of insulator plugs.

System and method for battery insulation

A cell module and modular cell tray apparatus for a modular electrochemical device that are more easily manufactured and serviced. A cell module is provided having a plurality of electrochemical cells. The cell module includes an electrically conductive carrier element having a plurality of apertures, wherein each aperture is configured to accept a top portion of an electrode body of an electrochemical cell. A modular cell tray apparatus is provided having a plurality of the cell modules. The cell tray apparatus includes an electrically insulating tray having rows of cell receptacles to accept the cell modules. A modular electrochemical device is provided having a plurality of the cell tray apparatuses. The modular electrochemical device includes a plurality of electrical connectors configured to electrically connect the cell modules within a cell tray apparatus, and to electrically connect the cell tray apparatuses to each other.

Modular high temperature battery electrical configurations

A system is employed to mount an electronic component on a shelf. A first restraining device is associated with a support structure in a first location. The first restraining device is configured to operably engage a mating piece associated with the electronic component. The support structure is configured to guide an electronic component along an axis of insertion when introduced to the shelf. A second restraining device is associated with the support structure in a second location. The second restraining device is configured to secure the electronic component via one or more fastening elements.

Restraint system for an energy storage device

A system for an electronic device includes a housing having one or more walls that define an internal region. An outlet port is fluidically coupled to the internal region of the housing, which allows emission of a fluid from the internal region of the housing as a first flow at a first temperature. A merging element, fluidically coupled to the outlet port, merges the first flow with a second flow, which has a second temperature that is less than the first temperature.

Systems and methods to thermally manage electronic devices

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Scotia, NY, United States of America

William Patrick Waters