Cambridge Isotope Laboratories, Inc.

William James Ryan

Richard C Titmas

William Wakefield Wood

Mark Donald Schwinden

Joel Chandler Bradley

Janusz Konrad Kozak

Marwan ElMasri

Salim Barkallah

Steven Michael Torkelson

This invention relates to lysine isotopologues of Formulas I and 1-A, as described herein, and processes for synthesizing the same and derivatives and intermediates involved therein. In one aspect, described herein is a chemical compound comprising an isotopically labeled analog, i.e., an isotopologue of a standard or naturally occurring lysine. The lysine isotopologue is synthetically formed to have stable isotopes of elements incorporated at selected positions. As such, the lysine isotopologue has a molecular mass different from the mass of a standard or naturally occurring lysine.

Lysine isotopologues, compositions comprising the same and methods of synthesis

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Westford, MA, United States of America

William James Ryan