Cardiac Pacemakers, Inc.

Boston Scientific Scimed, Inc.

Greatbatch Ltd.

Wilson Greatbatch Technologies, Inc.

William J Linder

Keith R Maile

Ron A Balczewski

Jeffrey E Stahmann

Imad Libbus

Andrew P Kramer

Michael John Kane

Jeffrey Allen Von Arx

Brendan Early Koop

Jacob M Ludwig

Mark D Amundson

Benjamin J Haasl

Scott R Stubbs

Nicholas J Stessman

David J Ternes

William Robert Mass

William L Zimmer

Scott Thomas Mazar

Brian L Schmidt

Kenneth Paul Hoyme

Hiten J Doshi

Aleksandra Kharam

Conrad L Sowder

James O Gilkerson

Michael J Lyden

Lynn H Elliott

David B Krig

Robert D Dreher

Jan D Wald

Allan Charles Shuros

Paul J Huelskamp

Robert S Harguth

Jeremy J Maniak

Douglas J Brandner

Benjamin Keith Stein

Krzysztof Z Siejko

Devon N Arnholt

Ramprasad Vijayagopal

Michael W Dooley

Gregory Scott Munson

Michael Wesley Paris

Arthur J Foster

Howard D Simms, Jr

Lance Eric Juffer

Moira B Sweeney

Douglas J Gifford

Brandon Tyler Keil

Angela M Muttonen

John D Hatlestad

James Kalgren

Paul Allan Haefner

Bin Mi

Nick A Youker

Prashant Brijmohansing Rawat

Doug M Birkholz

Rajesh Krishan Gandhi

Keith Johnson

Joseph M Bocek

Stephen John Hahn

Keith L Herrmann

John M Edgell

Amy Jean Brisben

James E Blood

Greg Paul Carpenter

Sarah Melissa Gruba

Jonathan H Kelly

Scot C Boon

Kenneth N Hayes

Bryan J Swackhamer

Thomas M Bocek

Daniel Joseph Landherr

Scott Dahl

Mark A Stockburger

Dan C Goldman

Ronald A Balczewski

Yinghong Yu

David L Perschbacher

Sunipa Saha

Allan Thomas Koshiol

Michael J Root

Scott R Vanderlinde

Abhi Chavan

Lawrence David Swanson

Jean M Bobgan

David W Kelly

John E Hansen

Thomas J Harris

Mark Gryzwa

Hal M Propp

Scott C Meyerson

Kevin Ely

Karen M Lent

John H Tangren

Jean-Cheui Hsung

Brandon Christopher Fellows

Boris Briskin

William A Palm

James Blilie

Richard J Wessels

Lloyd A Van Hofwegen

Improved devices, circuits and methods of operation in implantable stimulus systems. An implantable defibrillator may comprise an H-bridge output circuit having low and high sides, with a current controlling circuit coupled to the high side of the H-bridge output circuit and a current monitoring circuit coupled to the low side of the H-bridge output circuit. Alternate current paths to the output of the H-bridge, or to the H-Bridge itself, are used for delivering different therapies to the patient.

Output circuitry for multiple-therapy implantable devices

A medical device includes: a case at least a portion of which functions as a first electrode; a second electrode disposed in a header coupled to the case; a core assembly, the core assembly including operational circuitry enclosed within a core assembly housing, wherein the case includes the core assembly housing; and a battery assembly, the battery assembly including a battery enclosed within a battery housing, where the case further comprises the battery housing; where the operational circuitry is configured to drive a regulated voltage onto the case.

Case driven design for implantable medical device

Embodiments herein relate to a medical device for treating a cancerous tumor, the medical device having a first lead including a first wire and second wire; a second lead can include a third wire and fourth wire; and a first electrode in electrical communication with the first wire, a second electrode in electrical communication with the second wire, a third electrode in electrical communication with the third wire, and a fourth electrode in electrical communication with the fourth wire. The first and third electrodes form a supply electrode pair configured to deliver one or more electric fields to the cancerous tumor. The second and fourth electrodes form a sensing electrode pair configured to measure an impedance of the cancerous tumor independent of an impedance of the first electrode, the first wire, the third electrode, the third wire, and components in electrical communication therewith. Other embodiments are also included herein.

Electrical stimulation devices for cancer treatment

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having at least one electric field generating circuit configured to generate one or more electric fields; control circuitry in communication with the electric field generating circuit, the control circuitry configured to control delivery of the one or more electric fields from the at least one electric field generating circuit; and two or more electrodes to deliver the electric fields to the site of a cancerous tumor within a patient. At least one electrode can be configured to be implanted. At least one electrode can be configured to be external. The control circuitry can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz.

Electrical stimulation for cancer treatment with internal and external electrodes

An implantable medical device (IMD) is configured with a pressure sensor. The IMD includes a housing and a diaphragm that is exposed to the environment outside of the housing. The diaphragm is configured to transmit a pressure from the environment outside of the housing to a piezoelectric membrane. In response, the piezoelectric membrane generates a voltage and/or a current, which is representative of a pressure change applied to the housing diaphragm. In some cases, only changes in pressure over time are used, not absolute or gauge pressures.

Implantable medical device with pressure sensor

Improved devices, circuits and methods of operation in implantable stimulus systems. An implantable defibrillator may comprise a charging circuit using a transformer to store and build up energy on an HV capacitor or capacitor stack, with the HV capacitor in turn coupled to an H-bridge output circuit having low and high sides for issuing therapy. A current monitoring circuitry is provided on the low side of the H-Bridge and used to form a feedback loop to control current into a transformer that converts battery voltage to a signal that charges the HV capacitor to control current through the H-bridge.

High voltage therapy system with transformer primary current control

Various aspects of the present subject matter relate to an implantable device. Various device embodiments comprise at least one port to connect to at least one lead with at least electrode, stimulation circuitry connected to the at least one port and adapted to provide at least one neural stimulation therapy to at least one neural stimulation target using the at least one electrode, sensing circuitry connected to the at least one port and adapted to provide a sensed signal, and a controller connected to the stimulation circuitry to provide the at least one neural stimulation therapy and to the sensing circuitry to receive the sensed signal. In response to a triggering event, the controller is adapted to switch between at least two modes. Other aspects and embodiments are provided herein.

Implantable neural stimulator with mode switching

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit and control circuitry configured to control delivery of the one or more electric fields from the electric field generating circuit to the site of the cancerous tissue. An implantable lead is included having a lead body including a first electrical conductor disposed within the lead body, and a first electrode coupled to the lead body, the first electrode in electrical communication with the first electrical conductor, wherein the first electrical conductor forms part of an electrical circuit by which the electric fields from the electric field generating circuit are delivered to the site of the cancerous tissue, and the first electrode can include a conductive coil filar disposed around the lead body. Other embodiments are also included herein.

Electrodes for electrical stimulation to treat cancer

A ventricularly implantable medical device that includes a sensing module that is configured to detect an atrial fiducial and identify an atrial contraction based at least on part on the detected atrial fiducial. Control circuitry in the implantable medical device is configured to deliver a ventricular pacing therapy to a patient's heart based at least in part on the identified atrial contraction, and can automatically switch or revert the ventricular pacing therapies on the fly.

Leadless cardiac pacemaker with reversionary behavior

Improved devices, circuits and methods of operation in implantable stimulus systems. An implantable defibrillator may comprise a charging circuit using a transformer to store and build up energy on an HV capacitor or capacitor stack, with the HV capacitor in turn coupled to an H-bridge output circuit having low and high sides for issuing therapy. In the output current path, a current controlling circuitry is placed between the H-bridge and ground, allowing the greater flexibility in the selection of switching devices, and drivers for such devices, in the H-bridge circuit and/or enabling circuits between the H-bridge and the HV capacitor or other therapy circuit.

High voltage therapy system with low side control

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit configured to generate one or more electric fields and a control circuit in communication with the electric field generating circuit. The control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit. The system can include two or more electrodes to deliver the electric fields to a site of a cancerous tumor within a patient and a temperature sensor to measure the temperature of tissue at the site of the cancerous tumor. The control circuit can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.

Electrical stimulation with thermal treatment or thermal monitoring

A medical device includes a case and a core assembly. The core assembly includes operational circuitry enclosed within a core assembly housing. The medical device also includes a battery assembly, which includes a battery enclosed within a battery housing. The case includes the core assembly housing and the battery housing. A first electrode is coupled to, and electrically isolated from, the case; and a second electrode is electrically coupled to the case. The second electrode is electrically coupled to the operational circuitry via a sensing pathway that includes a portion of the case. The battery is electrically coupled to the operational circuitry via an energy supply pathway that includes the portion of the case.

Power noise reduction for an integrated battery

Growing community of inventors

Golden Valley, MN, United States of America

William J Linder