Other

Gelzone, Inc.

Miotox, LLC

Webco Partners, LLC

Binder, William J.

William J Binder

Edward C Leicht

David M Binder

Edward Leicht

Sotiria Mourkidou

The present specification discloses methods for treating a PTSD. The methods comprise extramuscularly administering a Botulinum toxin to an individual in one or more areas of a fronto-fascial layer located in a frontal head region, one or more areas of a temporoparietal-fascial layer located in a temporal head region, and one or more areas of an occipito-fascial layer located in an occipital head region. The methods further comprise extramuscularly administering a Botulinum toxin to one or more nerve exit points and/or one or more subcutaneous locations in the head and neck and/or one or more sites of an epicranial aponeurosis. The methods further comprise intramuscularly administering a Botulinum toxin to one or more locations within the left and right Splenius Capitis muscle, the left and right Masseter muscles, the left and right Trapezius muscles, or any combination thereof.

Zonal and targeted methods and uses for treating a post-traumatic stress disorder

The present specification discloses a method of augmenting or enhancing a chin of an individual comprising excising the left and right anterior mental fibrous condensation anteriorly and elevating the left and right medial mandibular and mandibulocutaneous ligaments to create an extended subperiosteal pocket as well as mandibular implants designed to be implanted using such methods.

Mandibular augmentation implants, methods, and uses

The present specification discloses methods and uses for treating a migraine disorder. The disclosed method comprising extramuscularly administering a Botulinum toxin to an individual in one of more areas of a fronto-fascial layer located in a frontal head region of the individual, one of more areas of a temporoparietal-fascial layer located in a temporal head region of the individual, and one or more areas of an occipito-fascial layer located in an occipital head region of the individual. The disclosed methods and uses further comprise extramuscularly administering a Botulinum toxin to one or more nerve exit points and/or one or more subcutaneous locations in the head and neck as well as one or more sites of an epicranial aponeurosis. The disclosed methods and uses further comprise intramuscularly administering a Botulinum toxin to one or more locations within the left and right Splenius Capitus muscle, the left and right Masseter muscles, the left and right Trapezius muscles, or any combination thereof.

Zonal and targeted methods and uses for treating a migraine disorder

The present invention provides a method for treating a patient for migraine headache, including symptoms associated with migraine head ache, such as migraine associated vertigo, which comprises administering to the patient a therapeutically effective amount of an invertebrate presynaptic neurotoxin, e.g. Botulinum toxin in a pharmaceutically safe form.

Treatment of migraine headaches with presynaptic neurotoxin

A method for selection and treatment of externally caused migraine headache, the method includes identifying a patient group having chronic migraine headache; determining the identified patient group, a specific patient with a post traumatic migraine headache; and administering to the selected patient by injection of a therapeutically effective amount of an invertebrate presynaptic neurotoxin in a pharmaceutically safe form to the selected patient's head or upper neck; administration preferably being on the sites of the trigeminal cervical system, enabling axonal transport of the neurotoxin from distal to central sites; and the administration preferably comprising extramuscular injection of the neurotoxin of suitable dilution (a) over the aponeurotic fascia to enable the neurotoxin to diffuse into distal sensory nerves, in order to concentrate the neurotoxin over the occipital-parietal-frontal head region, or (b) intra-orally, in a foramina of the sphenopalatine ganglion for enabling diffusion of the neurotoxin to the ganglion, or (c) to emerging exit points of nerves including foraminal sites for enabling the neurotoxin access to concentrated nerve bundles at exit points of the foramina.

Treatment of traumatic-induced migraine headache

The invention is a method for reducing the symptoms of vertigo. The method is performed by delivering a therapeutically effective amount of presynaptic neurotoxin, such as Botulinum Toxin A, in a pharmaceutically safe form to suitable locations around the head and neck.

Method of treating vertigo

A method for treating a patient with migraine headache includes administering to the patient a therapeutically effective amount of an invertebrate presynaptic neurotoxin in a pharmaceutically safe form. The administration includes extramuscular injection of the neurotoxin to emerging nerve points including foraminal sites for enabling neurotoxin access to concentrated nerve bundles at exit points of the foramina.

Treatment of migraine headache with diffusion of toxin in non-muscle related foraminal sites

A method for selection and treatment of externally caused migraine headache, the method includes identifying a patient group having chronic migraine headache; determining the identified patient group, a specific patient with a post traumatic migraine headache; and administering to the selected patient by injection of a therapeutically effective amount of a Botulinum neurotoxin in a pharmaceutically safe form to the selected patient's head or upper neck; administration preferably being on the sites of the trigeminal cervical system, enabling axonal transport of the neurotoxin from distal to central sites; and the administration preferably comprising extramuscular injection of the neurotoxin of suitable dilution (a) over the aponeurotic fascia, or (b) intra-orally, in a foramina of the sphenopalatine ganglion, or (c) to emerging exit points of nerves including foraminal sites.

Extramuscular treatment of traumatic-induced migraine headache

Methods of use of a multi-layer wrap, for providing more comfortable gel treatment to skin and pressure therapy for underlying skin, the wrap allowing for migration of moisture away from the skin while providing compressive musculo-skeletal support to the treatment site.

Gel wrap providing musculo-skeletal support

A multi-layer wrap, and method of use, for providing more comfortable gel treatment to skin and pressure therapy for underlying skin, the wrap allowing for migration of moisture away from the skin while providing compressive musculo-skeletal support to the treatment site.

A multi-layer wrap, for providing more comfortable gel treatment to skin while providing orthopedic support having a first layer of gel for contacting the skin and a second layer of an elastic and supportive loop portion of a hook and loop fastener, the wrap allowing for migration of moisture away from the skin. The wrap can be used as part of a suspension sleeve for use during arm surgery or post-operative recovery. The product is economically manufactured in the form of long rolls or as a sheet and is easily cut to any desired shape.

Arm suspension sleeve

A two-ply bandage for treatment of skin while providing orthopedic support having a first layer of gel for contacting the skin and a second layer of an elastic and supportive loop portion of a hook and loop fastener. The product is economically manufactured in the form of long rolls or as a sheet and is easily cut to any desired shape.

Growing community of inventors

Beverly Hills, CA, United States of America

William J Binder