Eli Lilly and Company

Anacor Pharmaceuticals, Inc.

William Hunter White

Jean Marie Defauw

Jacob J Plattner

Yong-Kang Zhang

Tsutomu Akama

Yasheen Zhou

Joseph Raymond Winkle

Shuhui Chen

Liang Chen

Ping Hu

Wentao Wu

Terry William Balko

Daniel Earl Snyder

Scott Dale Holmstrom

Zengyun An

Chongzhi Tang

Kurt Jarnagin

Jeffery Alan Meyer

Shon Roland Pulley

Yang Zhang

Joseph Winkle

Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. The claimed compounds are described by the following Markush formula: A typical example for a compound according to above formula is: A typical example for a compound according to above formula is: 

1-hydroxy-benzooxaboroles as antiparasitic agents

Provided are dihydroisoxazole compounds I useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. Also provided are compounds and processes useful for making the dihydroisoxazole compounds. wherein A is 

Parasiticidal dihydroisoxazole compounds

This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.

Boron-containing small molecules

Provided are novel methods and formulations for topically controlling ectoparasite infestations in animals using spinetoram or a pharmaceutically acceptable salt thereof.

Ectoparasiticidal methods and formulations

Boron containing small molecules

Provided are dihydroisoxazole compounds I useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. Also provided are compounds and processes useful for making the dihydroisoxazole compounds. 

This invention provides novel compounds, methods of using the compounds, and pharmaceutical compositions containing the compounds.

Boron-containing small molecules for controlling ectoparasites

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Greenfield, IN, United States of America

William Hunter White