American National Red Cross

Other

William H Drohan

Jean-Luc Maloisel

Martin James MacPhee

Shirley I Miekka

Dawson Beall

Annemarie H Ralston

Ingrid Drevin

Stanley A Friedman

Herbert Baumann

Valdislav Bayer

David Tuthill

The present invention relates to a haemostatic multilayer bandage that comprises preferably a thrombin layer between two fibrinogen layers. The dressing may contain other resorbable materials such as glycolic acid or lactic acid based polymers or copolymers. The inventive haemostatic bandage is useful for the treatment of wounded tissue.

Hemostatic sandwich bandage

The present invention introduces a class of compounds, 2-substituted carbonyl compounds, that are useful as disinfecting agents, and particularly useful in methods for the disinfection of biological fluids. Members of the class of compounds have been found to possess pathogen inactivating properties against a variety of pathogens. The compounds and methods disclosed herein are useful for disinfecting biological fluids such as blood and blood fractions, among others.

Method of inactivating pathogens

The methods of the present invention provide a simple means for separating active and inactive Alpha Proteinase Inhibitor (API). The methods further provide means for purifying API at high yield (&gt;70%), and at levels of purity (&gt;90%) and activity (&gt;90%) not heretofore available. Moreover, the methods of the present invention are simple (i.e., two chromatographic steps) and efficient; and are thus especially suitable to large scale purification processes. These methods will contribute substantially to alleviating the unmet demand for API for therapeutic purposes.

Method for purification of alpha-1 proteinase inhibitor

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Springfield, VA, United States of America

William H Drohan