General Electric Company

Ge Healthcare Bio-Sciences Corp.

General Electric Corporation Gmbh

Ge Healthcare Bioscience Bioprocess Corp.

Westinghouse Air Brake Technologies Corporation

Bl Technologies, Inc.

Global Life Sciences Solutions USA LLC

William Guy Morris

Radislav Alexandrovich Potyrailo

Cheryl Margaret Surman

Andrew Michael Leach

Vijay Singh

Scott Martell Boyette

Vincent Francis Pizzi

Gerard J Gach

Manuel Nyffeler

Caibin Xiao

Jon Albert Dieringer

Marc Brian Wisnudel

Steven Y Go

David James Monk

Prashant Vishwanath Shrikhande

William Chester Platt

LiJie Yu

Theodore J Cecconie

Charles L Dumoulin

Kenneth Brakeley Welles

Lembit Salasoo

Jeffrey Michael Ashe

Harold Woodruff Tomlinson, Jr

Biao Fang

Danian Zheng

Derek Lee Watkins

Ronald James Wroczynski

David Deloyd Anderson

Roger Neal Johnson

Jeffrey Bernard Fortin

Peter D Miller

Eric Lifshin

Bruce William Brisson

Patrick Edward Pastecki

Andrew David Pris

Ronald Eugene Shaffer

Tracy Lynn Paxon

William Patrick Flanagan

Amy Linsebigler Smentkowski

Subhasish Roychoudhury

Glenn Alfred Johnson

Mary Lynn Stanley

Katharine Dovidenko

Vincent F Pizzi

This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.

Method for preventing an unauthorized use of biprocess components

A sensor includes a resonant transducer, the resonant transducer being configured to determine the composition of an emulsion. The composition of the emulsion is determined by measuring the complex impedance spectrum values of the mixture of the emulsion and applying multivariate data analysis to the values.

Sensor systems for measuring an interface level in a multi-phase fluid composition

Method for preventing an unauthorized use of disposable bioprocess components

A system for measuring component fluid levels in a multi-phase fluid is provided. The system includes a sensing assembly. The sensing assembly includes a primary coil and at least one secondary coil. The primary coil is wound around a sampling container that holds the multi-phase fluid. The secondary coil is disposed proximate to the primary coil and each of the at least one secondary coil is electrically connected to at least one capacitive element. Further, the system includes an analyzer that is inductively coupled to the at least one secondary coil. The analyzer is configured to measure a response of the at least one secondary coil in response to an excitation signal provided to the primary coil.

System for measurement of fluid levels in multi-phase fluids

A system includes a vessel system for a fluid, a sampling assembly and a resonant sensor system coupled to the sampling assembly. The resonant sensor system may include a subsystem that detects a set of signals from a resonant sensor system at a plurality of locations in the vessel. The resonant sensor system may also include a subsystem that converts the set of signals to values of a complex impedance spectrum for the plurality of locations and stores the values of the complex impedance spectrum and frequency values. A subsystem determines a fluid phase inversion point from the values of the complex impedance spectrum.

Systems and methods for measuring an interface level in a multi-phase fluid composition

This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written into the memory chip, so that the information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.

Gamma sterilizable RFID system that prevents unauthorized operation of associated disposable bioprocess components

A field-portable impedance reader is provided. The impedance reader comprises a reader antenna, an impedance compensator, a calibrator, and a synchronous sampler. The impedance reader further comprises a digital processor that receives and processes signals from the synchronous sampler. Further, a wireless system comprising the impedance reader of the invention is provided.

Field-portable impedance reader and methods of making the same

An integrated interrogator for a RFID sensor is provided. The integrated interrogator comprises a digital reader in communication with the RFID sensor, an impedance reader in communication with the RFID sensor, and one or more controllers that coordinate actions of the digital reader and the impedance reader.

Methods and systems for integrated interrogation of RFID sensors

A boiling water reactor includes a reactor pressure vessel having a feedwater inlet for the introduction of recycled steam condensate and/or makeup coolant into the vessel, and a steam outlet for the discharge of produced steam for appropriate work. A fuel core is located within a lower area of the pressure vessel. The fuel core is surrounded by a core shroud spaced inward from the wall of the pressure vessel to provide an annular downcomer forming a coolant flow path between the vessel wall and the core shroud. A probe system that includes a combination of conductivity/resistivity probes and/or one or more time-domain reflectometer (TDR) probes is at least partially located within the downcomer. The probe system measures the coolant level and flow velocity within the downcomer.

System and method for determining coolant level and flow velocity in a nuclear reactor

A sensing device for sensing one or more conditions inside a container is provided. The sensing device comprises a radio frequency based sensor; a support for positioning the sensor in operative proximity to the inside of the container, and a pick-up coil in operative association with the sensor.

Disposable sensing device having radio frequency based sensor

An embodiment of the invention described herein is directed to a detection system utilizing at least one radiofrequency identification (RFID) sensor comprising: an RFID sensor comprising: a substrate; an antenna; a sensor material selected to be sensitive to one of chemical or biological environment; and a reader, wherein said reader is configured to measure a signal in the form of a complex impedance from said RFID tag wherein said signal comprises a plurality of frequencies and a frequency shift of the maximum of the imaginary part of the complex impedance, a frequency shift of the minimum of the imaginary part of the complex impedance, a frequency shift of the maximum of the real part of the complex impedance, and changes in magnitude of the real part of the complex impedance; and, wherein said complex impedance is related to a nature and a concentration of analyte species derived from multivariate analysis.

Chemical and biological sensors, systems and methods based on radio frequency identification

Embodiments of the invention include a wireless sensor, such as an RFID tag, that includes a substrate, an antenna disposed on the substrate, and an environmentally sensitive sensor material disposed over at least a portion of said substrate. Other embodiments an RFID tag and at least one antibody coupled to the RFID tag. The RFID tag includes a substrate, circuitry disposed on the substrate, and an antenna coupled to the substrate. The at least one antibody is capable of affecting the signals emanating from the RFID tag. Further embodiments include a detection system that includes a reader. Yet other embodiments include a method for detecting specific analytes. The method includes providing an RFID tag which emanates a first signal having a first frequency, and enabling the REID tag to emanate a second signal having a second frequency upon attraction of a specific analyte to the RFID tag.

A method for sensing physical, chemical, and biological characteristics of an environment is provided. The method comprises using a radio frequency identification (RFID) sensor component having a predetermined range of power initiation levels and having predetermined resonant circuit parameters comprising the steps of activating the RFID sensor component and determining whether a range of power levels, needed for activating the sensor component, is below the predetermined range of power initiation levels; sensing at least one of the physical, chemical, and biological characteristics of the environment; quantifying the sensed characteristic of the environment using one or more selected resonant parameters, wherein the selection of parameters is based in part on the range of power levels needed to activate the sensor.

Methods and systems for sensing upon radiation exposure

A sensor is provided. The sensor comprises at least one sensing device comprising a first electrode and a second electrode, and a gap defined as a distance between one or more facing inner surfaces of the first and second electrodes, wherein the gap distance at least in part determines a threshold of one or more sensed parameters, and an antenna in operative association with the sensing device.

Sensors having gap based sensing devices and methods of making and using the same

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Rexford, NY, United States of America

William Guy Morris