Eli Lilly and Company

Pocared Diagnostics Ltd.

Battelle Memorial Institute

Gas Research Institute

Neoprobe Corporation

Ortho-Clinical Diagnostics, Inc

Takeda Pharmaceutical Company Limited

Aptar Stelmi Sas

Philip Morris USA Inc.

Medrad, Inc.

Ic Surgical, Inc.

Neoproke Corporation

William Godwin Atterbury

John P Tallarico

Gal Ingber

John S Laudo

Thomas Alan Klausing

Dave Holley

Douglas E Boyd

Steven Michael Madland

Jason A Schaefer

Sherwood G Talbert

Daniel A Kramer

Jessica Diane Young

James E Dvorsky

Donald J Hackman

David Arthur Holley

Mark Lafever

Beth A Gahagan

Beverly Anne Piatt

Michael L Marshall

Andrew Thomas Snow

Corrie Bennison

Brian Charles Kelley

Jan B Yates

Joseph Daniel Dennis, Jr

Jeffrey L Ellis

Eric Hassenpflug

Russell H Barnes

Jonathan Gurfinkel

K Bryan Scott

Steven E Huckaby

John Paul Tallarico

Kevin Sadeski

Carol Stillman

Joseph D Dennis

Chad Edward Bouton

Raymond Francis Jakubowicz

Thomas D Haubert

Ghislain Fournier

Mickaël Swal

Donald James Moran, Jr

Michael Scott Ulrich

Mark Sawczuk

Christopher Paul McKenzie

John Tallarico

Shekhar Nimkar

Adam C Fox

James Alan Prescott

Beverly Ann Piatt

Michael L Dee

Gregory A Trees

Michael Anthony Lorenz

James A Prescott

Joseph A Juratovac

Scott Nicholas Danhof

R Reade Harpham

John Bartholomew

Francis J Sciulli, Jr

Timothy Mark Blum

Andrew Sweeney

Jeffrey Richard Held

Dennis P Hack

Mark Gerard Diller

Steve W Stracener

Jeremy M Harris

James B Gleeson

Peter Andrew Gaydos

David R Busick

Ludwin M Mora

Robert B McCown

Nile F Hartman

Russell Kittel

Ryan Somogye

Beth A Kizer

Stephen C Schmitt

William Harold Morrison, Jr

G Frederick Renner

Bobby Lee Walters

Felicia R Ruggeri

Daniel Duane Meek

Shannon Marie-Lynn Hoste

Charles J Mutschler

Steve Wilder

Jessica Diane Modlich

James Leamon

Lee R Van Dixhorn

Marty J Warnecke

Richard K Thatcher

Steven M Madland

William Anton Bowes

Jake Pyzza

Adam Fox

Jane O'Loughlin

Steve Madland

Larry Keith Hooks, Jr

Noah John Scott Lemire

Larry K Hooks, Jr

Michael Ko

Robert Jonathan Cain

Lawrence A Weinstein

A therapeutic agent delivery system comprises a housing. A therapeutic agent delivery assembly is carried by the housing. The therapeutic agent delivery assembly comprises a chamber having a passageway. A therapeutic agent is carried in the passageway, and a needle is in communication with the passageway. The therapeutic agent delivery assembly may be translatable relative to the housing from a stowed configuration to a deployed configuration. Actuation of a user input may translate the therapeutic agent delivery assembly from the stowed configuration to the deployed configuration. An input restraint may be rotatable relative to the housing from a first rotational configuration to a second rotational configuration. In the first rotational configuration the input restraint may inhibit actuation of the user input, and in the second rotational configuration the input restraint may permit actuation of the user input.

Devices and processes for delivery of therapeutic fluids

Portion of a drug delivery device

Drug delivery device

A therapeutic agent delivery system () includes a housing () and a drive wheel () rotatably carried by the housing. A plunger rod () may be rotatable with the drive wheel relative to the housing from a first rotational configuration to a second rotational configuration. The plunger rod may be translatable relative to the housing from a first translational configuration to a second translational configuration. A plunger restraint () may maintain the plunger rod in the first translational configuration when the plunger rod is disposed in the first rotational configuration. The plunger restraint may permit the plunger rod to translate to the second translational configuration when the plunger rod is disposed in the second rotational configuration. A needle may move from a stowed configuration to a deployed configuration by the plunger rod when the plunger rod moves from the first translational configuration to the second translational configuration.

Systems, devices, and processes for delivery of therapeutic fluids

An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier may include two identical parts that are discrete from one another and interlock with one another. Carrier includes a cushion to support the syringe. Protrusions may be provided on cushion to further support syringe. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

Medication injection system

The invention provides methods and apparatus for injecting a medicine, especially a highly viscous medicine. Conventional methods and apparatus for injecting viscous medicines suffers suffer from a variety of problems such as excessive force during the initial needle insertion and initial injection. In an inventive method, during the initial phase of the injection, energy is stored in a torsion spring that is subsequently released during a later stage of the injection. The present invention also provides for an improved autoinjector; especially via the use of a combination compression and torsion spring that powers the injection through controlling force applied to a plunger via a screw flange or nut having pins that ride in a prescribed path down the length of the autoinjector.

Process and autoinjector device for injections with increased patient comfort

Processes and devices provide parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that generates a gas. A device may include a first actuation chamber containing a first reagent, a second reaction chamber containing a second reagent, and a third therapeutic fluid chamber containing the therapeutic fluid. In a loaded configuration, a plunger separates the first chamber from the second chamber. In a delivery configuration, the plunger allows the first reagent from the first chamber to communicate and react with the second reagent from the second chamber. The generated gas acts upon a plunger to deliver the therapeutic fluid from the third chamber.

Processes and devices for delivery of fluid by chemical reaction

Autoinjectors and methods of injection are described that feature release mechanisms and/or end-of-dose sound which can operate in conjunction with a powered plunger to efficiently inject a controlled dose from a syringe.

Autoinjectors having advanced release and sound features

An autoinjector and method of injection are described. A power spring causes rotation of a drive nut about the central axis of the autoinjector that, in turn, causes a middle screw to rotate in the same direction as the drive nut and also to move in the distal direction while pushing a center screw in the distal direction that pushes the syringe and needle. The center screw also pushes a plunger that pushes the fluid out of the syringe. After injection, a locked retract screw is freed and rotates in the same direction as the middle screw causing the syringe to retract the syringe into the housing.

Autoinjector and method of injecting fluids

Fluid delivery device

Pusher foot for a fluid delivery device

Protective cap for injection needle

An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier includes two identical parts that are discrete from one another and interlock with one another. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

Automatic injection system

Growing community of inventors

Columbus, OH, United States of America

William Godwin Atterbury