Ortho-clinical Diagnostics, Inc

Eastman-kodak Company

Johnson & Johnson Clinical Diagnostics, Inc.

William Franklin Gottermeier

Andrew M Kirsch

Aaron Michael Swick

Zhong Ding

Raymond Francis Jakubowicz

Kory Adam Gunnerson

David Angelo Tomasso

Daniel P Salotto

James Ellis Robinson

Kory A Gunnerson

Raymond F Jakubowicz

David A Tomasso

Mark Elliott Deacon

Mark M Locey

Charles E Declerck

A sample collection device for a fluid includes: a substantially disk-shaped body having a periphery; a capillary channel extending through the body and bounded by the periphery, having a first end and a second end, wherein the first end is adapted to draw the fluid into the channel by capillary action; a sample collection well located in the vicinity of the second end and in fluid communication with the capillary channel; and an axis of rotation extending through the center of the disk and which is substantially perpendicular to the major surface of the disk-shaped body. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge having a housing comprising an air vent in fluid communication with the capillary channel when the disk is rotated in a first position.

Rotatable disk-shaped fluid sample collection device

An article of manufacture composed of tray-like packaging unit characterized by a first section designed to hold a sample analysis slide and a second section designed to hold a sample collection device. Molded into the tray-like packaging unit are a thermoformed well designed to accept a patient's liquid sample from a pipette or syringe, a splash wall formed between the first section and the second section designed to contain the patient's liquid sample in the thermoformed well, and an overflow reservoir designed to hold excess patient sample placed in the thermoformed well. Also molded into the sidewalls of tray-like packaging unit are projections designed to allow the sample analysis slide and the sample collection device to be snapped into the packaging unit resulting in a secure configuration for transport.

Packaging that facilitates sample collection

A sample collection device for a fluid sample includes: a body including a capillary channel having a first end and a second end, wherein the first end is adapted to draw the fluid into the channel by capillary action; an air vent located in the vicinity of the second end and in fluid communication with the capillary channel; a barrier positioned within the capillary channel to prevent flow of the fluid by capillary action thereacross; and features on opposing sides of the body to form an axis of rotation, which is substantially perpendicular to the overall direction of the capillary channel from the first end to the second end. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge having a sample manipulation device to bring the first end into position with the sample manipulation device.

Rotatable fluid sample collection device

An ion-junction fibrous bridge and a potentiometric test element incorporating the same, wherein the fibers extending generally along the center-line between two liquid access apertures in the bridge, are readily capable of conducting aqueous liquid through the bridge, and fibers extending at an angle of at least 20 .degree. from said center-line are not readily capable of conducting aqueous liquid.

Directional flow ion-junction bridge

A device is disclosed for determining ion activity in liquid solutions by the use of electrodes over which a cover sheet with an internal capillary bridge promotes ionic migration between the electrodes. The cover sheet is formed of a porous material ribbon encapsulated in a nonporous web. Preferably, the cover sheet is punched at each electrode to provide fluid access holes for receiving drops of liquid solutions.

Method of making capillary bridge in apparatus for determining ionic

Capillary bridge in apparatus for determining ionic activity

Biaxially-oriented, heatset polyester film is heat relaxed at a uniform temperature and supported buy impingement with gas such as air, while subjecting the film to low tension in its longitudinal dimension. Undesirable draw lines, as defined herein, are avoided by maintaining the longitudinal dimension of the film in an arcuate configuration composed of a single curve or serpentine succession of curves free of straight segments. Each such curve is characterized as having a radius of curvature in the range from about 1 inch to about 8 inches, subtending an arc of no less than 40.degree.. A serpentine configuration is preferred in which case the gas impinges upon alternate sides of the web. Temperatures of heat relaxation preferably are within the range from 30 to 100 centrigrade degrees higher than the polyester glass transition temperature.

Maintaining planarity in polyester film during uniform temperature heat

A thermosensitive image-forming element is comprised of at least one image-forming layer and a biaxially-oriented heatset poly(ethylene terephthalate) film support which is capable of resisting dimensional distortion resulting from the combined effects of tension and heat. The element is processed by application of heat sufficient to form a visible image while maintaining the element under tension in its longitudinal dimension and no tension in its transverse dimension.

Growing community of inventors

Pittsford, NY, United States of America

William Franklin Gottermeier