Schering-plough Healthcare Products Inc.

Other

Schering Corporation

William F Rencher

Joseph A Haslwanter

Suresh D Babu

Christopher H Day

Shankar Musunuri

James Schwing

Aqueous nasal spray compositions comprising a medicament and an aqueous carrier comprising water soluble polymers selected from the group consisting of polyvinylpyrrolidone and mixtures thereof.

Nasal spray compositions

A skin barrier lotion for protection against contact with irritants comprises: about 5 to 15 percent by weight of a long-chain fatty acid; about 1 to 5 percent by weight of a long-chain fatty alcohol; about 1 to 10 percent by weight of a hydrocarbon oil; about 1 to 30 percent by weight of a silicone skin protectant; about 0.5 to about 5 percent by weight of an alkanolamine; about 0.5 to about 5 percent by weight of a humectant; about 0.5 to about 10 percent by weight of an inorganic skin protectant; about 0.5 to 15 weight percent of a preservative; and about 50 to 90 percent by weight water. Optionally, the lotion will also contain up to about 5 percent by weight of a fragrance, odor neutralizer or a mixture thereof.

Skin barrier composition

Oxymetazoline HCI and/or chlorpheniramine maleate nasal spray compositions

Aqueous nasal spray compositions containing:

Nasal spray compositions exhibiting increased retention in the nasal

The present invention is directed to a novel sustained release matrix and oral dosage form comprising a homogeneous matrix formed from a wet granulation containing an effective amount of a medicament and a polymer blend of hydroxypropyl cellulose and hydroxyethyl cellulose. The present invention also discloses a novel process for making a sustained release oral dosage form comprising wet granulating a medicament with a polymer blend of hydroxypropyl cellulose and hydroxyethyl cellulose to form a homogeneous matrix, wherein the polymer blend is provided in an amount effective to control the release of said medicament, then forming the homogenous matrix into a solid oral dosage form.

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Cordova, TN, United States of America

William F Rencher