Vaxinnate Corporation

Curagen Corporation

Vaninnate Corporation

William F McDonald

Thomas J Powell

Langzhou Song

James W Huleatt

Valerian Nakaar

Duane D Hewitt

Henri Lichenstein

Richard August Shimkets

Meijia Yang

Compositions that include at least a portion of at least one pathogen-associated molecular pattern and at least a portion of at least one member selected from the group consisting of a Den1 viral envelope protein, a Den2 viral envelope protein, a Den3 viral envelope protein and a Den4 viral envelope protein are employed in methods to stimulate a protective immune response in a subject.

Methods of stimulating immunity employing dengue viral antigens

Methods of stimulating protective immunity employing Dengue viral antigens

Fusion proteins comprise at least a portion of at least one flagellin and at least a portion of at least one Dengue viral envelope protein. The fusion proteins are used to stimulate an immune response and protective immunity in a subject.

Fusion proteins comprising flagellin and dengue viral envelope proteins

Disclosed are osteoprotegerin-like polypeptides, nucleic acids encoding osteoprotegerin-like polypeptides, and methods of using these molecules. The osteoprotegerin-like polypeptides sequence homology to osteoprotegerin and tumor necrosis factor receptor molecules.

Nucleic acids encoding osteoprotegern-like proteins and methods of using same

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Cranbury, NJ, United States of America

William F McDonald