Humacyte, Inc

Other

William E Tente

Laura E Niklason

Justin T Strader

Shannon L M Dahl

Joseph J Lundquist

Juliana Blum

Heather L Prichard

Parrish M Galliher

Colin R Tuohey

Michael Edward Fisher

Patrick M Guertin

Joseph D Crowell

Shannon Dahl

Shannon Lm Dahl

Shannon LM Dahl

The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.

Tissue-engineered constructs

Tubular tissue-engineered constructs

A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions.

Tissue and organ graft bioreactor and method of operation

Growing community of inventors

Seekonk, MA, United States of America

William E Tente