Midwest Orthopaedic Research Foundation

University of Minnesota

Kensey Nash Corporation

Knc Ner Acquisition Sub, Inc.

Midwest Orthopedic Research Foundation

William D Lew

Ramon B Gustilo

Bruce P Lee

Jeffrey L Dalsin

John L Murphy

Laura Vollenweider

Fangmin Xu

Joan E Bechtold

Arinne N Lyman

Steven Chow

Richard S Hammett

Jediah White

Robert E Hunter

Michael Brodie

Curtis W Kowalczyk

Jeanne Virosco

Jed White

Jack L Lewis

The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins.

Adhesive compounds and methods use for hernia repair

The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.

Bioadhesive constructs

The present invention is a rotating track cutting guide system that maintains precise alignment of a bone saw with bone tissue. The rotating track cutting guide generally includes a track subassembly and cutting guide subassemblies attachable to the bone that is to be cut. The track subassembly supports an oscillating surgical saw driver. The track subassembly is removably securable to cutting guide subassemblies which are attachable to the desired bone to facilitate a series of controlled cuts. The design of the track subassembly stabilizes the oscillating saw driver and enables it to both rotate in the plane of the saw blade and move linearly along the track.

Rotating track cutting guide system

The invention provides surgical resection instruments, and methods of use, for facilitating accurately cut surfaces for the placement of femoral prosthesis components. The posterior condyles and anterior femoral cortex provide reference points for measurement and cuts of the femur with these instruments. One embodiment of the femoral resection instrument provides for precise anterior cuts of the femur appropriate for one of several sizes of prosthesis components without the need for separate cutting guides. Another embodiment provides for shifting the cutting location of both the posterior and anterior cuts by a portion of the distance between sizes of the prosthesis components while maintaining the reference position relative to the posterior part of the condyles and corresponding intercondylar notch. A third embodiment has an adjustable paddle so that the femoral resection instrument can be adjusted to the correct orientation when the femoral condyles are worn unequally. These various features may be combined, as desired. The invention includes related methods.

Device and method for distal femur cutting and prosthesis measuring

An adjustable trial prosthesis or prosthetic component provides a surgeon with the capability of efficiently and accurately examining a joint's functioning without having to remove a trial prosthesis insert and replace it with another sterilized insert. The adjustable trial has a first surface that approximates the top surface of the corresponding permanent prosthesis and a second surface that engages a bone. A distance adjustment mechanism can alter the distance between the first and second surfaces. The distance adjustment mechanism can include a screw oriented generally between the two surfaces or other distance adjustment mechanisms such as a fluid filled bladder. The adjustable trial can include force transducers to provide information on forces within the joint. To assist a surgeon with the alignment of portions of the musculo-skeletal system, a line of strong light is provided. The light source can be a laser or other suitable light source which is combined with appropriate optics. A balancing apparatus can be used to assess relative tensions on peri-articular soft tissue structures. The balance has a support that is adapted for rigid attachment directly or indirectly to a bone.

Arthroplasty trial prosthesis alignment devices and associated methods

A knee reconstruction apparatus and method provides for controlling and adjusting the point of fixation of a ligament graft, for example a replacement for the anterior cruciate ligament, which permits precisely and repeatably adjusting the length of the ligament graft or graft components with the joint under a prescribed load prior to fixation. A fixture is fixed on the tibia and includes an adjustable clamp that holds a ligament graft anchored or held in the femur. The clamp can be moved for adjusting the length of the ligament graft, or individual segments of a composite ligament graft while the joint is under a prescribed load. The load carried by one or more individual graft components also can be measured prior to fixation to ensure that each of the segments of a composite ligament graft will carry the desired or selected load for a joint under a prescribed load.

Ligament graft apparatus and method

Growing community of inventors

Mendota Heights, MN, United States of America

William D Lew