Applied Research Center, Inc.

Louisiana State University and Agricultural & Mechanical College

Musc Foundation for Research Development

Augusta University Research Institute, Inc.

Georgia Regents Research Institute, Inc.

William D Hill

George G Wicks

Paul M Weinberger

Samuel Herberg

Sudharsan Periyasamy-Thandavan

Methods and monodisperse glass microsphere composites comprising a porous wall hollow-glass microsphere; a cargo of a therapeutic is loaded inside of the porous wall hollow-glass microsphere; and a first shell fully encapsulating the porous wall hollow-glass microsphere and capping pores in the walls, retaining the cargo inside of the porous wall hollow-glass microsphere.

Method and devices for delivering therapeutics by oral, respiratory, mucosal, transdermal routes

Compositions and methods for glass composites suitable for tissue augmentation, biomedical, and cosmetic applications are provided. The glass microsphere component of the composites are biologically inert, non-reactive and act as a nearly permanent tissue filler. One embodiment provides a tissue augmentation composite containing an effective amount of solid glass microspheres, hollow glass microspheres, porous wall hollow glass microspheres, or combinations thereof with a suitable biocompatible matrix to serve as a bulking agent when injected into a patient. The compositions can be used for soft or hard tissue augmentation as well as delivery of cargos on demand.

Glass composites for tissue augmentation, biomedical and cosmetic applications

Compositions and methods for modulating miRNAs up-regulated or down-regulated in aged individuals and their downstream targets are disclosed. Methods of treating musculoskeletal disorders are also provided.

Compositions and methods for treating musculoskeletal diseases and disorders

Growing community of inventors

Augusta, GA, United States of America

William D Hill