University of Michigan

Cedars-Sinai Medical Center

University of California

William D Chey

James A Ashton-Miller

Brennan Spiegel

Gene Parunak

Adrienne Harris

Jason Baker

Brennan M R Spiegel

Eric D Shah

Aaron Miles Kehrer

An anorectal expulsion device includes a balloon having a wall that extends between proximal and distal ends of the balloon and defines a balloon interior. The balloon interior contains a self-expanding, low compression-set material (e.g., open cell foam). The device also includes a catheter that extends through the proximal end of the balloon and at least a portion of the balloon interior. An interior of the catheter is in fluid communication with the balloon interior. The device also includes a termination component (e.g., a cap or a valve) coupled to the catheter at a position along the catheter that is outside of and proximal to the proximal end of the balloon (e.g., at the proximal end of the catheter). The physical configuration of the termination component is adjustable, and controls whether the balloon interior is in fluid communication with the external environment.

Self-inflating anorectal expulsion device

Described herein are kits and methods for identifying the likelihood of having a food sensitivity or intolerance, and determining dietary modifications accordingly. For example, the likelihood of having sensitivities, intolerances or allergies to gluten, lactose, FODMAPs and others tested and calculated. Additionally, diet modifications can be determined according to the likelihood of particular sensitivities, and the effectiveness of diet modifications can be evaluated by monitoring of meals and subsequent symptoms, and evaluating the monitoring information. Through application of the methods herein, dietary intake and symptom data may be collected and aggregated to evaluate the effect or desirability of particular foods on a population of interest.

Methods and kits for identifying food sensitivities and intolerances

A probe system includes a finger-mountable housing having a distal end and a proximal receptacle end. The proximal receptacle end defines an opening to receive a finger. The probe system also includes a probe assembly disposed on or within the finger-mountable housing and having at least a first sensor. The first sensor is positioned to measure a physical characteristic of a first tissue when the finger-mountable housing and probe assembly are inserted in a rectum of the patient.

Digital manometry finger-mountable sensor device

Growing community of inventors

Ann Arbor, MI, United States of America

William D Chey